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Intact subepidermal nerve fibers mediate mechanical hypersensitivity via the activation of protein kinase C gamma in spared nerve injury
BACKGROUND: Spared nerve injury is an important neuropathic pain model for investigating the role of intact primary afferents in the skin on pain hypersensitivity. However, potential cellular mechanisms remain poorly understood. In phosphoinositide-3 kinase pathway, pyruvate dehydrogenase kinase 1 (...
Autores principales: | Ko, Miau-Hwa, Yang, Ming-Ling, Youn, Su-Chung, Lan, Chyn-Tair, Tseng, To-Jung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956387/ https://www.ncbi.nlm.nih.gov/pubmed/27296621 http://dx.doi.org/10.1177/1744806916656189 |
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