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Structural Insights into Arl1-Mediated Targeting of the Arf-GEF BIG1 to the trans-Golgi

The GTPase Arf1 is the major regulator of vesicle traffic at both the cis- and trans-Golgi. Arf1 is activated at the cis-Golgi by the guanine nucleotide exchange factor (GEF) GBF1 and at the trans-Golgi by the related GEF BIG1 or its paralog, BIG2. The trans-Golgi-specific targeting of BIG1 and BIG2...

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Detalles Bibliográficos
Autores principales:	Galindo, Antonio, Soler, Nicolas, McLaughlin, Stephen H., Yu, Minmin, Williams, Roger L., Munro, Sean
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956616/ https://www.ncbi.nlm.nih.gov/pubmed/27373159 http://dx.doi.org/10.1016/j.celrep.2016.06.022

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