Cargando…

Low neutrophil alkaline phosphatase score is a new aspect of calreticulin-mutated myeloproliferative neoplasms

Calreticulin (CALR) and JAK2-V617F gene mutations, which are major genetic mutations in patients with primary myelofibrosis (PMF) and essential thrombocythemia (ET), exert different effects on the clinical features and outcomes of these diseases. We analyzed 88 and 9 patients with ET and PMF, respec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kondo, Toshinori, Tasaka, Taizo, Tomioka, Nanako, Sano, Fuminori, Tokunaga, Hirotoshi, Suemori, Shin-ichiro, Tsujioka, Takayuki, Matsuhashi, Yoshiko, Nakanishi, Hidekazu, Wada, Hideho, Tohyama, Kaoru, Sugihara, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956637/ https://www.ncbi.nlm.nih.gov/pubmed/27504244 http://dx.doi.org/10.1186/s40064-016-2829-6

Ejemplares similares

Philadelphia chromosome-positive acute lymphoblastic leukemia with extramedullary and meningeal relapse after allogeneic hematopoietic stem cell transplantation that was successfully treated with dasatinib
por: Kondo, Toshinori, et al.
Publicado: (2014)

Analysis of Hereditary Elliptocytosis with Decreased Binding of Eosin-5-maleimide to Red Blood Cells
por: Suemori, Shin-ichiro, et al.
Publicado: (2015)

Successful Cord Blood Transplantation in a Werner Syndrome Patient with High-risk Myelodysplastic Syndrome
por: Hayashi, Kiyohito, et al.
Publicado: (2018)

Calreticulin Mutations in Myeloproliferative Neoplasms
por: Lavi, Noa
Publicado: (2014)

Mutant Calreticulin in the Myeloproliferative Neoplasms
por: Prins, Daniel, et al.
Publicado: (2020)

Withaferin A suppresses the growth of myelodysplasia and leukemia cell lines by inhibiting cell cycle progression
por: Okamoto, Shuichiro, et al.
Publicado: (2016)

Successful treatment with ABL tyrosine kinase inhibitor for patients with acute myeloid leukemia with BCR-ABL1
por: Takeuchi, Asako, et al.
Publicado: (2020)

Calreticulin Exon 9 Mutations in Myeloproliferative Neoplasms
por: Ha, Jung-Sook, et al.
Publicado: (2015)

Five-aza-2′-deoxycytidine-induced hypomethylation of cholesterol 25-hydroxylase gene is responsible for cell death of myelodysplasia/leukemia cells
por: Tsujioka, Takayuki, et al.
Publicado: (2015)

Secreted mutant calreticulins as rogue cytokines in myeloproliferative neoplasms
por: Pecquet, Christian, et al.
Publicado: (2023)

Calreticulin Mutations in Myeloproliferative Neoplasms: Comparison of Three Diagnostic Methods
por: Park, Ji-Hye, et al.
Publicado: (2015)

The Mutation Profile of Calreticulin in Patients with Myeloproliferative Neoplasms and Acute Leukemia
por: Wang, Jingyi, et al.
Publicado: (2016)

A novel assay to detect calreticulin mutations in myeloproliferative neoplasms
por: Rosso, Valentina, et al.
Publicado: (2016)

Mechanism underlying the development of myeloproliferative neoplasms through mutant calreticulin
por: Edahiro, Yoko, et al.
Publicado: (2020)

Rigosertib induces cell death of a myelodysplastic syndrome-derived cell line by DNA damage-induced G2/M arrest
por: Hyoda, Tomoko, et al.
Publicado: (2015)

Somatic mutations of calreticulin in a Brazilian cohort of patients with myeloproliferative neoplasms
por: Machado-Neto, João Agostinho, et al.
Publicado: (2015)

Calreticulin mutation-specific immunostaining in myeloproliferative neoplasms: pathogenetic insight and diagnostic value
por: Vannucchi, A M, et al.
Publicado: (2014)

The Expression of Myeloproliferative Neoplasm-Associated Calreticulin Variants Depends on the Functionality of ER-Associated Degradation
por: Mansier, Olivier, et al.
Publicado: (2019)

Production and Characterization of Peptide Antibodies to the C-Terminal of Frameshifted Calreticulin Associated with Myeloproliferative Diseases
por: Mughal, Farah Perveen, et al.
Publicado: (2022)

P1001: MODULATION OF MUTANT CALRETICULIN-DRIVEN ONCOGENESIS IN MYELOPROLIFERATIVE NEOPLASMS BY CLASSICAL HLA GENES
por: Shivarov, Velizar, et al.
Publicado: (2023)

VLX1570 induces apoptosis through the generation of ROS and induction of ER stress on leukemia cell lines
por: Kurozumi, Nami, et al.
Publicado: (2021)

Platelet function studies in myeloproliferative neoplasms patients with Calreticulin or JAK2(V617F) mutation
por: Guy, Alexandre, et al.
Publicado: (2023)

Calreticulin del52 and ins5 knock-in mice recapitulate different myeloproliferative phenotypes observed in patients with MPN
por: Benlabiod, Camélia, et al.
Publicado: (2020)

Induced Pluripotent Stem Cells Enable Disease Modeling and Drug Screening in Calreticulin del52 and ins5 Myeloproliferative Neoplasms
por: Secardin, Lise, et al.
Publicado: (2021)

Histone deacetylase inhibitor, panobinostat, exerts anti-proliferative effect with partial normalization from aberrant epigenetic states on granulosa cell tumor cell lines
por: Hazama, Yukiko, et al.
Publicado: (2022)

Calreticulin and the Heart
por: Groenendyk, Jody, et al.
Publicado: (2022)

Rapid, low cost and sensitive detection of Calreticulin mutations by a PCR based amplicon length differentiation assay for diagnosis of myeloproliferative neoplasms
por: Trung, Ngo Tat, et al.
Publicado: (2019)

Calreticulin Immunohistochemistry in Myeloproliferative Neoplasms - Evolution of a New Cost-Effective Diagnostic Tool: A Retrospective Study with Histological and Molecular Correlation
por: Roy, Sanjeet, et al.
Publicado: (2022)

P988: MUTANT CALRETICULIN AND JAK2V617F DRIVER MUTATIONS INDUCE DISTINCT MITOTIC DEFECTS IN MYELOPROLIFERATIVE NEOPLASMS
por: Holl, Kristin, et al.
Publicado: (2023)

Evaluation of vascular events in patients with myeloproliferative syndromes and mutations of either the januskinase-2 or calreticulin gene at the university hospital Krems from 2008 to 2015
por: Hintermair, Sarah, et al.
Publicado: (2018)

Calreticulin: Challenges Posed by the Intrinsically Disordered Nature of Calreticulin to the Study of Its Function
por: Varricchio, Lilian, et al.
Publicado: (2017)

Severe Colitis Associated with both Epstein-Barr Virus and Cytomegalovirus Reactivation in a Patient with Severe Aplastic Anemia
por: Matsumoto, Hiroshi, et al.
Publicado: (2014)

Comparison of Clinical and Hematological Parameters of Janus Kinase 2, Calreticulin or Myeloproliferative Leukemia Virus Oncogene Mutant Essential Thrombocythemia and Triple-Negative Essential Thrombocythemia
por: Yıldız, Jale, et al.
Publicado: (2022)

Therapeutic cancer vaccination against mutant calreticulin in myeloproliferative neoplasms induces expansion of specific T cells in the periphery but specific T cells fail to enrich in the bone marrow
por: Holmström, Morten Orebo, et al.
Publicado: (2023)

Rab27a Is Essential for the Formation of Neutrophil Extracellular Traps (NETs) in Neutrophil-Like Differentiated HL60 Cells
por: Kawakami, Tatsumi, et al.
Publicado: (2014)

Calreticulin Is Essential for Cardiac Development
por: Mesaeli, Nasrin, et al.
Publicado: (1999)

Functional specialization of calreticulin domains
por: Nakamura, Kimitoshi, et al.
Publicado: (2001)

Calreticulin Induces Dilated Cardiomyopathy
por: Lee, Dukgyu, et al.
Publicado: (2013)

The many faces of parasite calreticulin
por: Esperante, Diego, et al.
Publicado: (2023)

Calreticulin inhibits commitment to adipocyte differentiation
por: Szabo, Eva, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_f1bo7qn7bo13fevguqo6a7f002