Signal Transducer and Activator of Transcription 3/MicroRNA-21 Feedback Loop Contributes to Atrial Fibrillation by Promoting Atrial Fibrosis in a Rat Sterile Pericarditis Model

BACKGROUND—: Postoperative atrial fibrillation is a frequent complication in cardiac surgery. The aberrant activation of signal transducer and activator of transcription 3 (STAT3) contributes to the pathogenesis of atrial fibrillation. MicroRNA-21 (miR-21) promotes atrial fibrosis. Recent studies su...

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Detalles Bibliográficos
Autores principales: Huang, Zhengrong, Chen, Xiao-jun, Qian, Cheng, Dong, Qian, Ding, Dan, Wu, Qiong-feng, Li, Jing, Wang, Hong-fei, Li, Wei-hua, Xie, Qiang, Cheng, Xiang, Zhao, Ning, Du, Yi-mei, Liao, Yu-hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956678/
https://www.ncbi.nlm.nih.gov/pubmed/27406600
http://dx.doi.org/10.1161/CIRCEP.115.003396

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