Does diastolic dysfunction precede systolic dysfunction in trastuzumab-induced cardiotoxicity? Assessment with multigated radionuclide angiography (MUGA)

BACKGROUND: Trastuzumab is successfully used for the treatment of HER2-positive breast cancer. Because of its association with cardiotoxicity, LVEF is monitored by MUGA, though this is a relatively late measure of cardiac function. Diastolic dysfunction (DD) is believed to be an early predictor of c...

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Detalles Bibliográficos
Autores principales: Reuvekamp, E. J., Bulten, B. F., Nieuwenhuis, A. A., Meekes, M. R. A., de Haan, A. F. J., Tol, J., Maas, A. H. E. M., Elias-Smale, S. E., de Geus-Oei, L. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956716/
https://www.ncbi.nlm.nih.gov/pubmed/26048264
http://dx.doi.org/10.1007/s12350-015-0164-x

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