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Features of an altered AMPK metabolic pathway in Gilbert’s Syndrome, and its role in metabolic health
Energy metabolism, involving the ATP-dependent AMPK-PgC-Ppar pathway impacts metabolic health immensely, in that its impairment can lead to obesity, giving rise to disease. Based on observations that individuals with Gilbert’s syndrome (GS; UGT1A1(*)28 promoter mutation) are generally lighter, leane...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956769/ https://www.ncbi.nlm.nih.gov/pubmed/27444220 http://dx.doi.org/10.1038/srep30051 |