Parecoxib prevents early postoperative cognitive dysfunction in elderly patients undergoing total knee arthroplasty: A double-blind, randomized clinical consort study

BACKGROUND: Trial design neuroinflammation and postoperative pain after surgery are increasingly reported in association with postoperative cognitive dysfunction (POCD). Parecoxib, a selective cyclooxygenase (COX)-2 inhibitor, is used for postoperative analgesia for its potent anti-inflammatory and...

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Detalles Bibliográficos
Autores principales: Zhu, Yang-Zi, Yao, Rui, Zhang, Zhe, Xu, Hui, Wang, Li-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
3300
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956786/
https://www.ncbi.nlm.nih.gov/pubmed/27428192
http://dx.doi.org/10.1097/MD.0000000000004082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956786/
https://www.ncbi.nlm.nih.gov/pubmed/27428192
http://dx.doi.org/10.1097/MD.0000000000004082

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