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Parecoxib prevents early postoperative cognitive dysfunction in elderly patients undergoing total knee arthroplasty: A double-blind, randomized clinical consort study

BACKGROUND: Trial design neuroinflammation and postoperative pain after surgery are increasingly reported in association with postoperative cognitive dysfunction (POCD). Parecoxib, a selective cyclooxygenase (COX)-2 inhibitor, is used for postoperative analgesia for its potent anti-inflammatory and...

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Detalles Bibliográficos
Autores principales:	Zhu, Yang-Zi, Yao, Rui, Zhang, Zhe, Xu, Hui, Wang, Li-Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer Health 2016
Materias:	3300
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956786/ https://www.ncbi.nlm.nih.gov/pubmed/27428192 http://dx.doi.org/10.1097/MD.0000000000004082

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