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Association between body mass index and in-hospital outcomes: Analysis of the nationwide inpatient database

IMPORTANCE: Over one-third of American adults (36%) are obese and more than two-thirds (69%) are overweight. The impact of obesity on hospitalization outcomes is not well understood. OBJECTIVE: To examine the association between body mass index (BMI) and overall, cancer, chronic obstructive pulmonar...

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Autores principales: Akinyemiju, Tomi, Meng, Qingrui, Vin-Raviv, Neomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956812/
https://www.ncbi.nlm.nih.gov/pubmed/27428218
http://dx.doi.org/10.1097/MD.0000000000004189
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author Akinyemiju, Tomi
Meng, Qingrui
Vin-Raviv, Neomi
author_facet Akinyemiju, Tomi
Meng, Qingrui
Vin-Raviv, Neomi
author_sort Akinyemiju, Tomi
collection PubMed
description IMPORTANCE: Over one-third of American adults (36%) are obese and more than two-thirds (69%) are overweight. The impact of obesity on hospitalization outcomes is not well understood. OBJECTIVE: To examine the association between body mass index (BMI) and overall, cancer, chronic obstructive pulmonary disease (COPD), asthma, and cardiovascular disease (CVD)-specific in-hospital mortality; postsurgical complications; and hospital length of stay (LOS). DESIGN: Cross-sectional study. SETTING: Representative sample of US hospitals included in the Health Cost and Utilization Project Nationwide Inpatient Sample database. PARTICIPANTS: We obtained data for patients admitted with a primary diagnosis of cancer, COPD, asthma, and CVD. MAIN OUTCOME: In-hospital mortality, postsurgical complications, and hospital LOS. RESULTS: A total of 800,417 patients were included in this analysis. A higher proportion of Blacks (26.8%; 12.5%) and Whites (23.3%; 8.7%) had BMI of 40 to 49.9 and ≥50, respectively, compared with Hispanics (20.4%; 7.3%). Compared with normal BMI patients, the odds of in-hospital mortality increased 3.6-fold (odds ratio [OR] 3.62, 95% confidence interval [CI]: 3.37–3.89) for preobese patients, 6.5-fold (OR: 6.52, 95% CI: 5.79–7.34) for patients with BMI: 30 to 31.9, 7.5-fold (OR: 7.57, 95% CI: 6.67–8.59) for patients with BMI: 34 to 35.9, and 1.6- fold (OR: 1.77, 95% CI: 1.56–1.79) for patients with BMI ≥ 50. Compared with normal BMI patients, preobese and overweight patients had shorter hospital stays (β preobese: −1.58, 95% CI: −1.63, −1.52); however, no clear trends were observed for postsurgical complications. CONCLUSIONS: The majority of hospitalized patients in this analysis had a BMI > 30, and higher BMI was associated with increased risk of mortality and longer hospital stay.
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spelling pubmed-49568122016-08-02 Association between body mass index and in-hospital outcomes: Analysis of the nationwide inpatient database Akinyemiju, Tomi Meng, Qingrui Vin-Raviv, Neomi Medicine (Baltimore) 4400 IMPORTANCE: Over one-third of American adults (36%) are obese and more than two-thirds (69%) are overweight. The impact of obesity on hospitalization outcomes is not well understood. OBJECTIVE: To examine the association between body mass index (BMI) and overall, cancer, chronic obstructive pulmonary disease (COPD), asthma, and cardiovascular disease (CVD)-specific in-hospital mortality; postsurgical complications; and hospital length of stay (LOS). DESIGN: Cross-sectional study. SETTING: Representative sample of US hospitals included in the Health Cost and Utilization Project Nationwide Inpatient Sample database. PARTICIPANTS: We obtained data for patients admitted with a primary diagnosis of cancer, COPD, asthma, and CVD. MAIN OUTCOME: In-hospital mortality, postsurgical complications, and hospital LOS. RESULTS: A total of 800,417 patients were included in this analysis. A higher proportion of Blacks (26.8%; 12.5%) and Whites (23.3%; 8.7%) had BMI of 40 to 49.9 and ≥50, respectively, compared with Hispanics (20.4%; 7.3%). Compared with normal BMI patients, the odds of in-hospital mortality increased 3.6-fold (odds ratio [OR] 3.62, 95% confidence interval [CI]: 3.37–3.89) for preobese patients, 6.5-fold (OR: 6.52, 95% CI: 5.79–7.34) for patients with BMI: 30 to 31.9, 7.5-fold (OR: 7.57, 95% CI: 6.67–8.59) for patients with BMI: 34 to 35.9, and 1.6- fold (OR: 1.77, 95% CI: 1.56–1.79) for patients with BMI ≥ 50. Compared with normal BMI patients, preobese and overweight patients had shorter hospital stays (β preobese: −1.58, 95% CI: −1.63, −1.52); however, no clear trends were observed for postsurgical complications. CONCLUSIONS: The majority of hospitalized patients in this analysis had a BMI > 30, and higher BMI was associated with increased risk of mortality and longer hospital stay. Wolters Kluwer Health 2016-07-18 /pmc/articles/PMC4956812/ /pubmed/27428218 http://dx.doi.org/10.1097/MD.0000000000004189 Text en Copyright © 2016 the Author(s). Published by Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0, where it is permissible to download, share and reproduce the work in any medium, provided it is properly cited. The work cannot be changed in any way or used commercially. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle 4400
Akinyemiju, Tomi
Meng, Qingrui
Vin-Raviv, Neomi
Association between body mass index and in-hospital outcomes: Analysis of the nationwide inpatient database
title Association between body mass index and in-hospital outcomes: Analysis of the nationwide inpatient database
title_full Association between body mass index and in-hospital outcomes: Analysis of the nationwide inpatient database
title_fullStr Association between body mass index and in-hospital outcomes: Analysis of the nationwide inpatient database
title_full_unstemmed Association between body mass index and in-hospital outcomes: Analysis of the nationwide inpatient database
title_short Association between body mass index and in-hospital outcomes: Analysis of the nationwide inpatient database
title_sort association between body mass index and in-hospital outcomes: analysis of the nationwide inpatient database
topic 4400
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956812/
https://www.ncbi.nlm.nih.gov/pubmed/27428218
http://dx.doi.org/10.1097/MD.0000000000004189
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