Cargando…

αT-Catenin Is a Constitutive Actin-binding α-Catenin That Directly Couples the Cadherin·Catenin Complex to Actin Filaments

α-Catenin is the primary link between the cadherin·catenin complex and the actin cytoskeleton. Mammalian αE-catenin is allosterically regulated: the monomer binds the β-catenin·cadherin complex, whereas the homodimer does not bind β-catenin but interacts with F-actin. As part of the cadherin·catenin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wickline, Emily D., Dale, Ian W., Merkel, Chelsea D., Heier, Jonathon A., Stolz, Donna B., Kwiatkowski, Adam V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957052/ https://www.ncbi.nlm.nih.gov/pubmed/27231342 http://dx.doi.org/10.1074/jbc.M116.735423

Ejemplares similares

α-Catenin–mediated cadherin clustering couples cadherin and actin dynamics
por: Chen, Chi-Shuo, et al.
Publicado: (2015)

Molecular mechanism for direct actin force-sensing by α-catenin
por: Mei, Lin, et al.
Publicado: (2020)

Distinct intramolecular interactions regulate autoinhibition of vinculin binding in αT-catenin and αE-catenin
por: Heier, Jonathon A., et al.
Publicado: (2021)

αE-catenin regulates actin dynamics independently of cadherin-mediated cell–cell adhesion
por: Benjamin, Jacqueline M., et al.
Publicado: (2010)

αE-catenin actin-binding domain alters actin filament conformation and regulates binding of nucleation and disassembly factors
por: Hansen, Scott D., et al.
Publicado: (2013)

Involvement of ZO-1 in Cadherin-based Cell Adhesion through Its Direct Binding to α Catenin and Actin Filaments
por: Itoh, Masahiko, et al.
Publicado: (1997)

Unraveling the mechanism of the cadherin-catenin-actin catch bond
por: Adhikari, Shishir, et al.
Publicado: (2018)

α-catenin, vinculin, and F-actin in strengthening E-cadherin cell–cell adhesions and mechanosensing
por: Dufour, Sylvie, et al.
Publicado: (2013)

Mechanism of the cadherin–catenin F-actin catch bond interaction
por: Wang, Amy, et al.
Publicado: (2022)

The nematode α-catenin ortholog, HMP1, has an extended α-helix when bound to actin filaments
por: Rangarajan, Erumbi S., et al.
Publicado: (2022)

Structural basis of αE-catenin–F-actin catch bond behavior
por: Xu, Xiao-Ping, et al.
Publicado: (2020)

Reevaluating αE-catenin monomer and homodimer functions by characterizing E-cadherin/αE-catenin chimeras
por: Bianchini, Julie M., et al.
Publicado: (2015)

Vinculin Is Part of the Cadherin–Catenin Junctional Complex: Complex Formation between α-Catenin and Vinculin
por: Weiss, Elisabeth E., et al.
Publicado: (1998)

Quantitative analysis of cadherin-catenin-actin reorganization during development of cell-cell adhesion
Publicado: (1996)

β-catenin regulates muscle glucose transport via actin remodelling and M-cadherin binding
por: Masson, Stewart W.C., et al.
Publicado: (2020)

The adhesion modulation domain of Caenorhabditis elegans α-catenin regulates actin binding during morphogenesis
por: Shao, Xiangqiang, et al.
Publicado: (2019)

α-Catenin links integrin adhesions to F-actin to regulate ECM mechanosensing and rigidity dependence
por: Mukherjee, Abhishek, et al.
Publicado: (2022)

Regulation of Classical Cadherin Membrane Expression and F-Actin Assembly by Alpha-Catenins, during Xenopus Embryogenesis
por: Nandadasa, Sumeda, et al.
Publicado: (2012)

α-Catenin contributes to the strength of E-cadherin–p120 interactions
por: Troyanovsky, Regina B., et al.
Publicado: (2011)

Expression of E-cadherin, α-catenin, and β-catenin in the process of lymph node metastasis in oral squamous cell carcinoma
por: Tanaka, N, et al.
Publicado: (2003)

Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions
por: Ishiyama, Noboru, et al.
Publicado: (2018)

Cadherins and catenins in cancer: connecting cancer pathways and tumor microenvironment
por: Lin, Wan-Hsin, et al.
Publicado: (2023)

Vinculin anchors contractile actin to the cardiomyocyte adherens junction
por: Merkel, Chelsea D., et al.
Publicado: (2019)

αT-catenin: A developmentally dispensable, disease-linked member of the α-catenin family
por: Chiarella, Sergio E., et al.
Publicado: (2018)

Scribble and α-Catenin cooperatively regulate epithelial homeostasis and growth
por: Huang, Yunxian, et al.
Publicado: (2022)

Phosphorylation Reduces the Mechanical Stability of the α‐Catenin/ β‐Catenin Complex
por: Le, Shimin, et al.
Publicado: (2019)

Expression of α-catenin in α-catenin–deficient cells increases resistance to sphingosine-induced apoptosis
por: Matsubara, Shyuichiro, et al.
Publicado: (2001)

p120-catenin and β-catenin differentially regulate cadherin adhesive function
por: Oas, Rebecca G., et al.
Publicado: (2013)

The cadherin–catenin complex in nasopharyngeal carcinoma
por: Galera-Ruiz, H., et al.
Publicado: (2011)

Functional Domains of α-Catenin Required for the Strong State of Cadherin-based Cell Adhesion
por: Imamura, Yuzo, et al.
Publicado: (1999)

α-Catenin Dependent E-cadherin Adhesion Dynamics as Revealed by an Accelerated Force Ramp
por: Bush, Joshua, et al.
Publicado: (2023)

The roles of catenins in the cadherin-mediated cell adhesion: functional analysis of E-cadherin-alpha catenin fusion molecules
Publicado: (1994)

Antagonism of Cell Adhesion by an α-Catenin Mutant, and of the Wnt-signaling Pathway by α-Catenin in Xenopus Embryos
por: Sehgal, Ravinder N.M., et al.
Publicado: (1997)

Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor
Publicado: (1994)

Mechanical stability of αT-catenin and its activation by force for vinculin binding
por: Pang, Si Ming, et al.
Publicado: (2019)

Cooperation between tropomyosin and α-actinin inhibits fimbrin association with actin filament networks in fission yeast
por: Christensen, Jenna R, et al.
Publicado: (2019)

α-catenin switches between a slip and an asymmetric catch bond with F-actin to cooperatively regulate cell junction fluidity
por: Arbore, C., et al.
Publicado: (2022)

E-cadherin and α-, β- and γ-catenin expression in prostate cancers: correlation with tumour invasion
por: Morita, N, et al.
Publicado: (1999)

Expression of S100A4, E-cadherin, α- and β-catenin in breast cancer biopsies
por: Pedersen, K B, et al.
Publicado: (2002)

beta-Catenin associates with the actin-bundling protein fascin in a noncadherin complex
Publicado: (1996)

Cannot write session to /tmp/vufind_sessions/sess_5vfbg59tqv8p96gv29h4124qag