On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver

Iron is an essential component of the erythrocyte protein hemoglobin and is crucial to oxygen transport in vertebrates. In the steady state, erythrocyte production is in equilibrium with erythrocyte removal(1). In various pathophysiological conditions, however, erythrocyte life span is severely comp...

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Detalles Bibliográficos
Autores principales: Theurl, Igor, Hilgendorf, Ingo, Nairz, Manfred, Tymoszuk, Piotr, Haschka, David, Asshoff, Malte, He, Shun, Gerhardt, Louisa M. S., Holderried, Tobias A. W., Seifert, Markus, Sopper, Sieghart, Fenn, Ashley M., Anzai, Atsushi, Rattik, Sara, McAlpine, Cameron, Theurl, Milan, Wieghofer, Peter, Iwamoto, Yoshiko, Weber, Georg F., Harder, Nina K., Chousterman, Benjamin G., Arvedson, Tara L., McKee, Mary, Wang, Fudi, Lutz, Oliver M. D., Rezoagli, Emanuele, Babitt, Jodie L., Berra, Lorenzo, Prinz, Marco, Nahrendorf, Matthias, Weiss, Guenter, Weissleder, Ralph, Lin, Herbert Y., Swirski, Filip K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957133/
https://www.ncbi.nlm.nih.gov/pubmed/27428900
http://dx.doi.org/10.1038/nm.4146

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