Cargando…

Lutein acts via multiple antioxidant pathways in the photo-stressed retina

Lutein slows the progression of age-related macular degeneration (AMD), a leading cause of blindness in ageing societies. However, the underlying mechanisms remain elusive. Here, we evaluated lutein’s effects on light-induced AMD-related pathological events. Balb/c mice exposed to light (2000 lux, 3...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kamoshita, Mamoru, Toda, Eriko, Osada, Hideto, Narimatsu, Toshio, Kobayashi, Saori, Tsubota, Kazuo, Ozawa, Yoko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957151/ https://www.ncbi.nlm.nih.gov/pubmed/27444056 http://dx.doi.org/10.1038/srep30226

Ejemplares similares

Neuroprotective Effects of Lutein in the Retina
por: Ozawa, Yoko, et al.
Publicado: (2012)

Neuroprotective effect of bilberry extract in a murine model of photo-stressed retina
por: Osada, Hideto, et al.
Publicado: (2017)

Neuroprotective Effect of 4-Phenylbutyric Acid against Photo-Stress in the Retina
por: Guzmán Mendoza, Naymel Alejandra, et al.
Publicado: (2021)

The Neuroprotective Effect of Rapamycin as a Modulator of the mTOR-NF-κB Axis during Retinal Inflammation
por: Okamoto, Tomohiro, et al.
Publicado: (2016)

Neuroprotective effect of activated 5′-adenosine monophosphate-activated protein kinase on cone system function during retinal inflammation
por: Kamoshita, Mamoru, et al.
Publicado: (2016)

Aquaporin 4 Suppresses Neural Hyperactivity and Synaptic Fatigue and Fine-Tunes Neurotransmission to Regulate Visual Function in the Mouse Retina
por: Ozawa, Yoko, et al.
Publicado: (2019)

Neuroprotective role of retinal SIRT3 against acute photo-stress
por: Ban, Norimitsu, et al.
Publicado: (2017)

Effects of Epigenetic Modification of PGC-1α by a Chemical Chaperon on Mitochondria Biogenesis and Visual Function in Retinitis Pigmentosa
por: Ozawa, Yoko, et al.
Publicado: (2022)

Taurine rescues mitochondria-related metabolic impairments in the patient-derived induced pluripotent stem cells and epithelial-mesenchymal transition in the retinal pigment epithelium
por: Homma, Kohei, et al.
Publicado: (2021)

ADIPOR1 deficiency-induced suppression of retinal ELOVL2 and docosahexaenoic acid levels during photoreceptor degeneration and visual loss
por: Osada, Hideto, et al.
Publicado: (2021)

Dietary Spirulina Supplementation Protects Visual Function From Photostress by Suppressing Retinal Neurodegeneration in Mice
por: Okamoto, Tomohiro, et al.
Publicado: (2019)

Angiopoietin-like Protein 2 Is a Multistep Regulator of Inflammatory Neovascularization in a Murine Model of Age-related Macular Degeneration
por: Hirasawa, Manabu, et al.
Publicado: (2016)

Renin–angiotensin system impairs macrophage lipid metabolism to promote age-related macular degeneration in mouse models
por: Nagai, Norihiro, et al.
Publicado: (2020)

Non-responsiveness to intravitreal aflibercept treatment in neovascular age-related macular degeneration: implications of serous pigment epithelial detachment
por: Nagai, Norihiro, et al.
Publicado: (2016)

AMPK-NF-κB Axis in the Photoreceptor Disorder during Retinal Inflammation
por: Kamoshita, Mamoru, et al.
Publicado: (2014)

Neural Degeneration in the Retina of the Streptozotocin-Induced Type 1 Diabetes Model
por: Ozawa, Yoko, et al.
Publicado: (2011)

Photo-stability of lutein in surfactant-free lutein-zein composite colloidal particles
por: de Boer, Frankjen Ynske, et al.
Publicado: (2019)

Dynamic changes in choroidal conditions during anti-vascular endothelial growth factor therapy in polypoidal choroidal vasculopathy
por: Nagai, Norihiro, et al.
Publicado: (2019)

Possible influences of lutein and zeaxanthin on the developing retina
por: Zimmer, J Paul, et al.
Publicado: (2007)

Lutein/Zeaxanthin Isomers and Quercetagetin Combination Safeguards the Retina from Photo-Oxidative Damage by Modulating Neuroplasticity Markers and the Nrf2 Pathway
por: Sahin, Emre, et al.
Publicado: (2023)

Benefits of aflibercept treatment for age-related macular degeneration patients with good best-corrected visual acuity at baseline
por: Minami, Sakiko, et al.
Publicado: (2018)

QD laser eyewear as a visual field aid in a visual field defect model
por: Iyama, Chigusa, et al.
Publicado: (2019)

Predictive factors of better outcomes by monotherapy of an antivascular endothelial growth factor drug, ranibizumab, for diabetic macular edema in clinical practice
por: Sato, Shinri, et al.
Publicado: (2017)

Why has Nature Chosen Lutein and Zeaxanthin to Protect the Retina?
por: Widomska, Justyna, et al.
Publicado: (2014)

Angiotensin II Type 1 Receptor Signaling Contributes to Synaptophysin Degradation and Neuronal Dysfunction in the Diabetic Retina
por: Kurihara, Toshihide, et al.
Publicado: (2008)

Correlation between Macular Pigment Optical Density and Neural Thickness and Volume of the Retina
por: Nagai, Norihiro, et al.
Publicado: (2020)

Physiological Significance of the Heterogeneous Distribution of Zeaxanthin and Lutein in the Retina of the Human Eye
por: Grudzinski, Wojciech, et al.
Publicado: (2023)

Neurodegenerative influence of oxidative stress in the retina of a murine model of diabetes
por: Sasaki, M., et al.
Publicado: (2010)

Ocular and Systemic Effects of Antioxidative Supplement Use in Young and Healthy Adults: Real-World Cross-Sectional Data
por: Minami, Sakiko, et al.
Publicado: (2020)

Retinal circulation time/arm-to-retina time ratio in the fluorescein angiography to evaluate retina-specific hemodynamics
por: Mushiga, Yasuaki, et al.
Publicado: (2022)

Absolute and estimated values of macular pigment optical density in young and aged Asian participants with or without age-related macular degeneration
por: Ozawa, Yoko, et al.
Publicado: (2017)

Retinal inflammation diagnosed as an idiopathic macular hole with multiple recurrences and spontaneous closures: A case report
por: Hayashi, Isami, et al.
Publicado: (2019)

Oxidative stress in the light-exposed retina and its implication in age-related macular degeneration
por: Ozawa, Yoko
Publicado: (2020)

Regulation of Posttranscriptional Modification as a Possible Therapeutic Approach for Retinal Neuroprotection
por: Ozawa, Yoko, et al.
Publicado: (2011)

Vision Loss by Central Retinal Vein Occlusion After Kaatsu Training: A Case Report
por: Ozawa, Yoko, et al.
Publicado: (2015)

Dynamic changes in neural retinal images during the development of a lamellar macular hole: A case report
por: Ozawa, Yoko, et al.
Publicado: (2019)

Effects of lutein or lutein in combination with vitamin C on mRNA expression and activity of antioxidant enzymes and status of the antioxidant system in SD rats
por: Song, Min-Hae, et al.
Publicado: (2015)

Renin-Angiotensin System Hyperactivation Can Induce Inflammation and Retinal Neural Dysfunction
por: Kurihara, Toshihide, et al.
Publicado: (2012)

Optic neuropathy causing vertical unilateral hemianopsia after pars plana vitrectomy for a macular hole: A case report
por: Kawashima, Hirohiko, et al.
Publicado: (2018)

Bisretinoids of the Retina: Photo-Oxidation, Iron-Catalyzed Oxidation, and Disease Consequences
por: Kim, Hye Jin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_20uvf3s17v22li04dof7iv1pr7