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Prognostic relevance of autophagy-related markers LC3, p62/sequestosome 1, Beclin-1 and ULK1 in colorectal cancer patients with respect to KRAS mutational status

BACKGROUND: Autophagy is a cellular pathway that regulates transportation of cytoplasmic macromolecules and organelles to lysosomes for degradation. Autophagy is involved in both tumorigenesis and tumour suppression. Here we investigated the potential prognostic value of the autophagy-related protei...

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Detalles Bibliográficos
Autores principales:	Schmitz, Klaus Juergen, Ademi, Ceflije, Bertram, Stefanie, Schmid, Kurt Werner, Baba, Hideo Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957418/ https://www.ncbi.nlm.nih.gov/pubmed/27444698 http://dx.doi.org/10.1186/s12957-016-0946-x

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