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Predicting Falls and When to Intervene in Older People: A Multilevel Logistical Regression Model and Cost Analysis

INTRODUCTION: Falls are the leading cause of injury in older people. Reducing falls could reduce financial pressures on health services. We carried out this research to develop a falls risk model, using routine primary care and hospital data to identify those at risk of falls, and apply a cost analy...

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Autores principales: Smith, Matthew I., de Lusignan, Simon, Mullett, David, Correa, Ana, Tickner, Jermaine, Jones, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957756/
https://www.ncbi.nlm.nih.gov/pubmed/27448280
http://dx.doi.org/10.1371/journal.pone.0159365
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author Smith, Matthew I.
de Lusignan, Simon
Mullett, David
Correa, Ana
Tickner, Jermaine
Jones, Simon
author_facet Smith, Matthew I.
de Lusignan, Simon
Mullett, David
Correa, Ana
Tickner, Jermaine
Jones, Simon
author_sort Smith, Matthew I.
collection PubMed
description INTRODUCTION: Falls are the leading cause of injury in older people. Reducing falls could reduce financial pressures on health services. We carried out this research to develop a falls risk model, using routine primary care and hospital data to identify those at risk of falls, and apply a cost analysis to enable commissioners of health services to identify those in whom savings can be made through referral to a falls prevention service. METHODS: Multilevel logistical regression was performed on routinely collected general practice and hospital data from 74751 over 65’s, to produce a risk model for falls. Validation measures were carried out. A cost-analysis was performed to identify at which level of risk it would be cost-effective to refer patients to a falls prevention service. 95% confidence intervals were calculated using a Monte Carlo Model (MCM), allowing us to adjust for uncertainty in the estimates of these variables. RESULTS: A risk model for falls was produced with an area under the curve of the receiver operating characteristics curve of 0.87. The risk cut-off with the highest combination of sensitivity and specificity was at p = 0.07 (sensitivity of 81% and specificity of 78%). The risk cut-off at which savings outweigh costs was p = 0.27 and the risk cut-off with the maximum savings was p = 0.53, which would result in referral of 1.8% and 0.45% of the over 65’s population respectively. Above a risk cut-off of p = 0.27, costs do not exceed savings. CONCLUSIONS: This model is the best performing falls predictive tool developed to date; it has been developed on a large UK city population; can be readily run from routine data; and can be implemented in a way that optimises the use of health service resources. Commissioners of health services should use this model to flag and refer patients at risk to their falls service and save resources.
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spelling pubmed-49577562016-08-08 Predicting Falls and When to Intervene in Older People: A Multilevel Logistical Regression Model and Cost Analysis Smith, Matthew I. de Lusignan, Simon Mullett, David Correa, Ana Tickner, Jermaine Jones, Simon PLoS One Research Article INTRODUCTION: Falls are the leading cause of injury in older people. Reducing falls could reduce financial pressures on health services. We carried out this research to develop a falls risk model, using routine primary care and hospital data to identify those at risk of falls, and apply a cost analysis to enable commissioners of health services to identify those in whom savings can be made through referral to a falls prevention service. METHODS: Multilevel logistical regression was performed on routinely collected general practice and hospital data from 74751 over 65’s, to produce a risk model for falls. Validation measures were carried out. A cost-analysis was performed to identify at which level of risk it would be cost-effective to refer patients to a falls prevention service. 95% confidence intervals were calculated using a Monte Carlo Model (MCM), allowing us to adjust for uncertainty in the estimates of these variables. RESULTS: A risk model for falls was produced with an area under the curve of the receiver operating characteristics curve of 0.87. The risk cut-off with the highest combination of sensitivity and specificity was at p = 0.07 (sensitivity of 81% and specificity of 78%). The risk cut-off at which savings outweigh costs was p = 0.27 and the risk cut-off with the maximum savings was p = 0.53, which would result in referral of 1.8% and 0.45% of the over 65’s population respectively. Above a risk cut-off of p = 0.27, costs do not exceed savings. CONCLUSIONS: This model is the best performing falls predictive tool developed to date; it has been developed on a large UK city population; can be readily run from routine data; and can be implemented in a way that optimises the use of health service resources. Commissioners of health services should use this model to flag and refer patients at risk to their falls service and save resources. Public Library of Science 2016-07-22 /pmc/articles/PMC4957756/ /pubmed/27448280 http://dx.doi.org/10.1371/journal.pone.0159365 Text en © 2016 Smith et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Smith, Matthew I.
de Lusignan, Simon
Mullett, David
Correa, Ana
Tickner, Jermaine
Jones, Simon
Predicting Falls and When to Intervene in Older People: A Multilevel Logistical Regression Model and Cost Analysis
title Predicting Falls and When to Intervene in Older People: A Multilevel Logistical Regression Model and Cost Analysis
title_full Predicting Falls and When to Intervene in Older People: A Multilevel Logistical Regression Model and Cost Analysis
title_fullStr Predicting Falls and When to Intervene in Older People: A Multilevel Logistical Regression Model and Cost Analysis
title_full_unstemmed Predicting Falls and When to Intervene in Older People: A Multilevel Logistical Regression Model and Cost Analysis
title_short Predicting Falls and When to Intervene in Older People: A Multilevel Logistical Regression Model and Cost Analysis
title_sort predicting falls and when to intervene in older people: a multilevel logistical regression model and cost analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957756/
https://www.ncbi.nlm.nih.gov/pubmed/27448280
http://dx.doi.org/10.1371/journal.pone.0159365
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