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Optical coherence tomography (OCT) angiography findings in retinal arterial macroaneurysms

BACKGROUND: Optical coherence tomography angiography is a novel imaging technique that allows dyeless in vivo visualization of the retinal and choroidal vasculature. The purpose of this study was to describe optical coherence tomography (OCT) angiography findings in patients with retinal arterial ma...

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Autores principales: Alnawaiseh, Maged, Schubert, Friederike, Nelis, Pieter, Wirths, Gabriele, Rosentreter, André, Eter, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957854/
https://www.ncbi.nlm.nih.gov/pubmed/27449320
http://dx.doi.org/10.1186/s12886-016-0293-2
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author Alnawaiseh, Maged
Schubert, Friederike
Nelis, Pieter
Wirths, Gabriele
Rosentreter, André
Eter, Nicole
author_facet Alnawaiseh, Maged
Schubert, Friederike
Nelis, Pieter
Wirths, Gabriele
Rosentreter, André
Eter, Nicole
author_sort Alnawaiseh, Maged
collection PubMed
description BACKGROUND: Optical coherence tomography angiography is a novel imaging technique that allows dyeless in vivo visualization of the retinal and choroidal vasculature. The purpose of this study was to describe optical coherence tomography (OCT) angiography findings in patients with retinal arterial macroaneurysms (RAMs). METHODS: Three eyes of three patients with RAMs were retrospectively included. Fundus photography, OCT, fluorescein angiography (FA), and OCT angiography were performed. The entire imaging data was analyzed in detail. RESULTS: OCT angiography could detect the RAMs noninvasively without dye injection. By simultaneously observing the OCT scans, it was possible to determine the depth of the RAMs in the retina, to detect the exact localization in relation to the main vessel, and to determine the level of blood flow in the RAMs. CONCLUSIONS: OCT angiography can clearly visualize RAMs without use of a dye. It also allows layer-specific observation of blood flow in each layer of the RAM. OCT angiography provides additional dynamic information on RAMs, which is not obtained with FA and facilitates a better understanding of its morphology and activity. This information in combination with ICG and fluorescein angiography can help to optimize direct laser treatment.
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spelling pubmed-49578542016-07-23 Optical coherence tomography (OCT) angiography findings in retinal arterial macroaneurysms Alnawaiseh, Maged Schubert, Friederike Nelis, Pieter Wirths, Gabriele Rosentreter, André Eter, Nicole BMC Ophthalmol Research Article BACKGROUND: Optical coherence tomography angiography is a novel imaging technique that allows dyeless in vivo visualization of the retinal and choroidal vasculature. The purpose of this study was to describe optical coherence tomography (OCT) angiography findings in patients with retinal arterial macroaneurysms (RAMs). METHODS: Three eyes of three patients with RAMs were retrospectively included. Fundus photography, OCT, fluorescein angiography (FA), and OCT angiography were performed. The entire imaging data was analyzed in detail. RESULTS: OCT angiography could detect the RAMs noninvasively without dye injection. By simultaneously observing the OCT scans, it was possible to determine the depth of the RAMs in the retina, to detect the exact localization in relation to the main vessel, and to determine the level of blood flow in the RAMs. CONCLUSIONS: OCT angiography can clearly visualize RAMs without use of a dye. It also allows layer-specific observation of blood flow in each layer of the RAM. OCT angiography provides additional dynamic information on RAMs, which is not obtained with FA and facilitates a better understanding of its morphology and activity. This information in combination with ICG and fluorescein angiography can help to optimize direct laser treatment. BioMed Central 2016-07-22 /pmc/articles/PMC4957854/ /pubmed/27449320 http://dx.doi.org/10.1186/s12886-016-0293-2 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Alnawaiseh, Maged
Schubert, Friederike
Nelis, Pieter
Wirths, Gabriele
Rosentreter, André
Eter, Nicole
Optical coherence tomography (OCT) angiography findings in retinal arterial macroaneurysms
title Optical coherence tomography (OCT) angiography findings in retinal arterial macroaneurysms
title_full Optical coherence tomography (OCT) angiography findings in retinal arterial macroaneurysms
title_fullStr Optical coherence tomography (OCT) angiography findings in retinal arterial macroaneurysms
title_full_unstemmed Optical coherence tomography (OCT) angiography findings in retinal arterial macroaneurysms
title_short Optical coherence tomography (OCT) angiography findings in retinal arterial macroaneurysms
title_sort optical coherence tomography (oct) angiography findings in retinal arterial macroaneurysms
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957854/
https://www.ncbi.nlm.nih.gov/pubmed/27449320
http://dx.doi.org/10.1186/s12886-016-0293-2
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