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IKKβ-mediated inflammatory myeloid cell activation exacerbates experimental autoimmune encephalomyelitis by potentiating Th1/Th17 cell activation and compromising blood brain barrier

BACKGROUND: The inflammatory myeloid cell activation is one of the hallmarks of experimental autoimmune encephalomyelitis (EAE), yet the in vivo role of the inflammatory myeloid cell activation in EAE has not been clearly resolved. It is well-known that IKK/NF-κB is a key signaling pathway that regu...

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Detalles Bibliográficos
Autores principales:	Lee, Min Jung, Bing, So Jin, Choi, Jonghee, Jang, Minhee, Lee, Gihyun, Lee, Hyunkyoung, Chang, Byung Soo, Jee, Youngheun, Lee, Sung Joong, Cho, Ik-Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957872/ https://www.ncbi.nlm.nih.gov/pubmed/27450563 http://dx.doi.org/10.1186/s13024-016-0116-1

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