Cargando…

Oridonin inhibits pancreatic cancer cell migration and epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling pathway

BACKGROUND: Oridonin (ORI) can inhibit proliferation and migration in various types of cancer cell lines. However, the exact mechanism remains unclear. We investigated the migration inhibitory effect of ORI on human pancreatic cancer SW1990 cells and dissected the possible molecular mechanism(s). ME...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Qian-Qian, Chen, Ke, Ye, Qiao, Jiang, Xiao-Hua, Sun, Yun-Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957915/ https://www.ncbi.nlm.nih.gov/pubmed/27453691 http://dx.doi.org/10.1186/s12935-016-0336-z

Ejemplares similares

NCAPG facilitates colorectal cancer cell proliferation, migration, invasion and epithelial–mesenchymal transition by activating the Wnt/β-catenin signaling pathway
por: Shi, Yanlong, et al.
Publicado: (2022)

Knockdown of AGGF1 inhibits the invasion and migration of gastric cancer via epithelial–mesenchymal transition through Wnt/β-catenin pathway
por: Yao, Han-Hui, et al.
Publicado: (2019)

CCR9 initiates epithelial–mesenchymal transition by activating Wnt/β-catenin pathways to promote osteosarcoma metastasis
por: Kong, Haoran, et al.
Publicado: (2021)

EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway
por: Zhang, Rui, et al.
Publicado: (2020)

The lncRNA DLX6-AS1 promoted cell proliferation, invasion, migration and epithelial-to-mesenchymal transition in bladder cancer via modulating Wnt/β-catenin signaling pathway
por: Guo, Jinan, et al.
Publicado: (2019)

Inactivation of the Wnt/β-catenin signaling pathway underlies inhibitory role of microRNA-129-5p in epithelial–mesenchymal transition and angiogenesis of prostate cancer by targeting ZIC2
por: Jiang, Zhenming, et al.
Publicado: (2019)

Heparanase potentiates the invasion and migration of pancreatic cancer cells via epithelial-to-mesenchymal transition through the Wnt/β-catenin pathway
por: Wang, Cheng, et al.
Publicado: (2020)

Emodin Inhibits Colon Cancer Cell Invasion and Migration by Suppressing Epithelial–Mesenchymal Transition via the Wnt/β-Catenin Pathway
por: Gu, Juan, et al.
Publicado: (2019)

MID1 and MID2 regulate cell migration and epithelial-mesenchymal transition via modulating Wnt/β-catenin signaling
por: Qiao, Yingying, et al.
Publicado: (2020)

Cadherin 13 Inhibits Pancreatic Cancer Progression and Epithelial-mesenchymal Transition by Wnt/β-Catenin Signaling
por: Xu, Dengfei, et al.
Publicado: (2020)

LncRNA LEF1-AS1 promotes metastasis of prostatic carcinoma via the Wnt/β-catenin pathway
por: Li, Weiyuan, et al.
Publicado: (2020)

Wnt/β-catenin signaling pathway is involved in induction of apoptosis by oridonin in colon cancer COLO205 cells
por: Bu, Heqi, et al.
Publicado: (2019)

Overexpression of mircoRNA-137 inhibits cervical cancer cell invasion, migration and epithelial–mesenchymal transition by suppressing the TGF-β/smad pathway via binding to GREM1
por: Miao, Hui, et al.
Publicado: (2019)

TACR2 is associated with the immune microenvironment and inhibits migration and proliferation via the Wnt/β-catenin signaling pathway in prostate cancer
por: Jianfeng, Wang, et al.
Publicado: (2021)

LncRNA FLVCR1-AS1 promotes proliferation, migration and activates Wnt/β-catenin pathway through miR-381-3p/CTNNB1 axis in breast cancer
por: Pan, Zhiyu, et al.
Publicado: (2020)

Cyclin G2 inhibits epithelial-to-mesenchymal transition by disrupting Wnt/β-catenin signaling
por: Bernaudo, S, et al.
Publicado: (2016)

LncRNA CBR3-AS1 potentiates Wnt/β-catenin signaling to regulate lung adenocarcinoma cells proliferation, migration and invasion
por: Hou, Min, et al.
Publicado: (2021)

DKK1 inhibits breast cancer cell migration and invasion through suppression of β-catenin/MMP7 signaling pathway
por: Niu, Jie, et al.
Publicado: (2019)

IQGAP1 promotes pancreatic cancer progression and epithelial-mesenchymal transition (EMT) through Wnt/β-catenin signaling
por: Hu, Wei, et al.
Publicado: (2019)

Oridonin inhibits the migration and epithelial‐to‐mesenchymal transition of small cell lung cancer cells by suppressing FAK‐ERK1/2 signalling pathway
por: Xu, Linhao, et al.
Publicado: (2020)

EFEMP2 suppresses epithelial-mesenchymal transition via Wnt/β-catenin signaling pathway in human bladder cancer
por: Zhou, Qiang, et al.
Publicado: (2019)

MicroRNA‐148a‐3p suppresses epithelial‐to‐mesenchymal transition and stemness properties via Wnt1‐mediated Wnt/β‐catenin pathway in pancreatic cancer
por: Fu, Xiaowei, et al.
Publicado: (2020)

Absence of EpCAM in cervical cancer cells is involved in sluginduced epithelial‐mesenchymal transition
por: Liu, Xian, et al.
Publicado: (2021)

MARVELD3 inhibits the epithelial‐mesenchymal transition and cell migration by suppressing the Wnt/β‐catenin signaling pathway in non–small cell lung cancer cells
por: Li, Shirong, et al.
Publicado: (2023)

Erratum: Cyclin G2 inhibits epithelial-to-mesenchymal transition by disrupting Wnt/β-catenin signalling
por: Bernaudo, S, et al.
Publicado: (2016)

MicroRNAs target the Wnt/β-catenin signaling pathway to regulate epithelial-mesenchymal transition in cancer
por: Lei, Yuhe, et al.
Publicado: (2020)

A Positive Role of Cadherin in Wnt/β-Catenin Signalling during Epithelial-Mesenchymal Transition
por: Howard, Sara, et al.
Publicado: (2011)

Fascin Induces Epithelial-Mesenchymal Transition of Cholangiocarcinoma Cells by Regulating Wnt/β-Catenin Signaling
por: Mao, Xianhai, et al.
Publicado: (2016)

Tre2 (USP6NL) promotes colorectal cancer cell proliferation via Wnt/β-catenin pathway
por: Sun, Kang, et al.
Publicado: (2019)

[Retracted] MicroRNA‑148a suppresses epithelial‑mesenchymal transition and invasion of pancreatic cancer cells by targeting Wnt10b and inhibiting the Wnt/β‑catenin signaling pathway
por: Peng, Long, et al.
Publicado: (2023)

FERMT1 contributes to the migration and invasion of nasopharyngeal carcinoma through epithelial–mesenchymal transition and cell cycle arrest
por: Li, Lingling, et al.
Publicado: (2022)

YPEL3 suppresses epithelial–mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway
por: Zhang, Jian, et al.
Publicado: (2016)

RORα Suppresses Epithelial-to-Mesenchymal Transition and Invasion in Human Gastric Cancer Cells via the Wnt/β-Catenin Pathway
por: Su, Jian, et al.
Publicado: (2019)

Arctigenin Suppressed Epithelial-Mesenchymal Transition Through Wnt3a/β-Catenin Pathway in PQ-Induced Pulmonary Fibrosis
por: Gao, Fei, et al.
Publicado: (2020)

EFEMP2 suppresses epithelial-mesenchymal transition via Wnt/β-catenin signaling pathway in human bladder cancer: Erratum
por: Zhou, Qiang, et al.
Publicado: (2022)

HNRNPA2B1 regulates the epithelial–mesenchymal transition in pancreatic cancer cells through the ERK/snail signalling pathway
por: Dai, Shengjie, et al.
Publicado: (2017)

METTL3 attenuates proliferative vitreoretinopathy and epithelial‐mesenchymal transition of retinal pigment epithelial cells via wnt/β‐catenin pathway
por: Ma, Xinqi, et al.
Publicado: (2021)

Jatrorrhizine inhibits colorectal carcinoma proliferation and metastasis through Wnt/β-catenin signaling pathway and epithelial–mesenchymal transition
por: Wang, Pan, et al.
Publicado: (2019)

PlGF knockdown attenuates hypoxia-induced stimulation of cell proliferation and glycolysis of lung adenocarcinoma through inhibiting Wnt/β-catenin pathway
por: Zhang, Wei, et al.
Publicado: (2021)

The role of Wnt/β-catenin-lin28a/let-7 axis in embryo implantation competency and epithelial-mesenchymal transition (EMT)
por: Li, Qian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_rf75gap7sts38uaeon6sanu3gd