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Prediction and verification of novel peptide targets of protein tyrosine phosphatase 1B

Phosphotyrosine peptides are useful starting points for inhibitor design and for the search for protein tyrosine phosphatase (PTP) phosphoprotein substrates. To identify novel phosphopeptide substrates of PTP1B, we developed a computational prediction protocol based on a virtual library of protein s...

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Detalles Bibliográficos
Autores principales: Li, Xun, Köhn, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957924/
https://www.ncbi.nlm.nih.gov/pubmed/27025565
http://dx.doi.org/10.1016/j.bmc.2016.03.030

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