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Periarticular injection of liposomal bupivacaine in total knee arthroplasty

The purpose of this study was to determine whether the use of a periarticular injection using liposomal bupivacaine could decrease pain and improve outcomes after total knee arthroplasty. Fifty consecutive patients received no periarticular injections (group A). Another 50 consecutive patients recei...

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Detalles Bibliográficos
Autores principales: Webb, Bradley T., Spears, J. Reid, Smith, Langan S., Malkani, Arthur L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958110/
https://www.ncbi.nlm.nih.gov/pubmed/28326386
http://dx.doi.org/10.1016/j.artd.2015.09.001
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author Webb, Bradley T.
Spears, J. Reid
Smith, Langan S.
Malkani, Arthur L.
author_facet Webb, Bradley T.
Spears, J. Reid
Smith, Langan S.
Malkani, Arthur L.
author_sort Webb, Bradley T.
collection PubMed
description The purpose of this study was to determine whether the use of a periarticular injection using liposomal bupivacaine could decrease pain and improve outcomes after total knee arthroplasty. Fifty consecutive patients received no periarticular injections (group A). Another 50 consecutive patients received a periarticular injection of liposomal bupivacaine (group B). There were no differences in the groups with respect to gender, age, body mass index (BMI), or comorbidities. There was a significant reduction in the amount of narcotics used in the liposomal bupivacaine group (60.97-mg oral morphine equivalent vs 89.74 mg, P = 0.009). Patients in group B with a BMI <40 and a Charlson comorbidity index of 0-3 had decreased length of stay (2.64 vs 3.06 days, P = .004), narcotic use over 24-48 hours (110.66 vs 182.47 mg, P = .013), and narcotic use over 48-72 hours (49.61 vs. 112.65 mg, P = .004). In patients with a BMI <40 and comorbidity index of ≤3, periarticular injection using liposomal bupivacaine leads to earlier discharge along with decreased use of narcotics.
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spelling pubmed-49581102017-03-21 Periarticular injection of liposomal bupivacaine in total knee arthroplasty Webb, Bradley T. Spears, J. Reid Smith, Langan S. Malkani, Arthur L. Arthroplasty Today Original Research The purpose of this study was to determine whether the use of a periarticular injection using liposomal bupivacaine could decrease pain and improve outcomes after total knee arthroplasty. Fifty consecutive patients received no periarticular injections (group A). Another 50 consecutive patients received a periarticular injection of liposomal bupivacaine (group B). There were no differences in the groups with respect to gender, age, body mass index (BMI), or comorbidities. There was a significant reduction in the amount of narcotics used in the liposomal bupivacaine group (60.97-mg oral morphine equivalent vs 89.74 mg, P = 0.009). Patients in group B with a BMI <40 and a Charlson comorbidity index of 0-3 had decreased length of stay (2.64 vs 3.06 days, P = .004), narcotic use over 24-48 hours (110.66 vs 182.47 mg, P = .013), and narcotic use over 48-72 hours (49.61 vs. 112.65 mg, P = .004). In patients with a BMI <40 and comorbidity index of ≤3, periarticular injection using liposomal bupivacaine leads to earlier discharge along with decreased use of narcotics. Elsevier 2015-10-12 /pmc/articles/PMC4958110/ /pubmed/28326386 http://dx.doi.org/10.1016/j.artd.2015.09.001 Text en Copyright © 2015 Published by Elsevier Inc. on behalf of American Association of Hip and Knee Surgeons. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Research
Webb, Bradley T.
Spears, J. Reid
Smith, Langan S.
Malkani, Arthur L.
Periarticular injection of liposomal bupivacaine in total knee arthroplasty
title Periarticular injection of liposomal bupivacaine in total knee arthroplasty
title_full Periarticular injection of liposomal bupivacaine in total knee arthroplasty
title_fullStr Periarticular injection of liposomal bupivacaine in total knee arthroplasty
title_full_unstemmed Periarticular injection of liposomal bupivacaine in total knee arthroplasty
title_short Periarticular injection of liposomal bupivacaine in total knee arthroplasty
title_sort periarticular injection of liposomal bupivacaine in total knee arthroplasty
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958110/
https://www.ncbi.nlm.nih.gov/pubmed/28326386
http://dx.doi.org/10.1016/j.artd.2015.09.001
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