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Investigation of Elimination Rate, Persistent Subpopulation Removal, and Relapse Rates of Mycobacterium tuberculosis by Using Combinations of First-Line Drugs in a Modified Cornell Mouse Model
Currently, the most effective tuberculosis control method involves case finding and 6 months of chemotherapy. There is a need to improve our understanding about drug interactions, combination activities, and the ability to remove persistent bacteria using the current regimens, particularly in relati...
Autores principales: | Hu, Yanmin, Pertinez, Henry, Ortega-Muro, Fatima, Alameda-Martin, Laura, Liu, Yingjun, Schipani, Alessandro, Davies, Geraint, Coates, Anthony |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958161/ https://www.ncbi.nlm.nih.gov/pubmed/27216065 http://dx.doi.org/10.1128/AAC.02548-15 |
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