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First Report of bla(IMP-14) on a Plasmid Harboring Multiple Drug Resistance Genes in Escherichia coli Sequence Type 131
The bla(IMP-14) carbapenem resistance gene has largely previously been observed in Pseudomonas aeruginosa and Acinetobacter spp. As part of global surveillance and sequencing of carbapenem-resistant Escherichia coli, we identified a sequence type 131 strain harboring bla(IMP-14) within a class 1 int...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958194/ https://www.ncbi.nlm.nih.gov/pubmed/27246777 http://dx.doi.org/10.1128/AAC.00840-16 |
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author | Stoesser, Nicole Sheppard, Anna E. Peirano, Gisele Sebra, Robert P. Lynch, Tarah Anson, Luke W. Kasarskis, Andrew Motyl, Mary R. Crook, Derrick W. Pitout, Johann D. |
author_facet | Stoesser, Nicole Sheppard, Anna E. Peirano, Gisele Sebra, Robert P. Lynch, Tarah Anson, Luke W. Kasarskis, Andrew Motyl, Mary R. Crook, Derrick W. Pitout, Johann D. |
author_sort | Stoesser, Nicole |
collection | PubMed |
description | The bla(IMP-14) carbapenem resistance gene has largely previously been observed in Pseudomonas aeruginosa and Acinetobacter spp. As part of global surveillance and sequencing of carbapenem-resistant Escherichia coli, we identified a sequence type 131 strain harboring bla(IMP-14) within a class 1 integron, itself nested within an ∼54-kb multidrug resistance region on an epidemic IncA/C(2) plasmid. The emergence of bla(IMP-14) in this context in the ST131 lineage is of potential clinical concern. |
format | Online Article Text |
id | pubmed-4958194 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | American Society for Microbiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-49581942016-07-26 First Report of bla(IMP-14) on a Plasmid Harboring Multiple Drug Resistance Genes in Escherichia coli Sequence Type 131 Stoesser, Nicole Sheppard, Anna E. Peirano, Gisele Sebra, Robert P. Lynch, Tarah Anson, Luke W. Kasarskis, Andrew Motyl, Mary R. Crook, Derrick W. Pitout, Johann D. Antimicrob Agents Chemother Epidemiology and Surveillance The bla(IMP-14) carbapenem resistance gene has largely previously been observed in Pseudomonas aeruginosa and Acinetobacter spp. As part of global surveillance and sequencing of carbapenem-resistant Escherichia coli, we identified a sequence type 131 strain harboring bla(IMP-14) within a class 1 integron, itself nested within an ∼54-kb multidrug resistance region on an epidemic IncA/C(2) plasmid. The emergence of bla(IMP-14) in this context in the ST131 lineage is of potential clinical concern. American Society for Microbiology 2016-07-22 /pmc/articles/PMC4958194/ /pubmed/27246777 http://dx.doi.org/10.1128/AAC.00840-16 Text en Copyright © 2016 Stoesser et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (http://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Epidemiology and Surveillance Stoesser, Nicole Sheppard, Anna E. Peirano, Gisele Sebra, Robert P. Lynch, Tarah Anson, Luke W. Kasarskis, Andrew Motyl, Mary R. Crook, Derrick W. Pitout, Johann D. First Report of bla(IMP-14) on a Plasmid Harboring Multiple Drug Resistance Genes in Escherichia coli Sequence Type 131 |
title | First Report of bla(IMP-14) on a Plasmid Harboring Multiple Drug Resistance Genes in Escherichia coli Sequence Type 131 |
title_full | First Report of bla(IMP-14) on a Plasmid Harboring Multiple Drug Resistance Genes in Escherichia coli Sequence Type 131 |
title_fullStr | First Report of bla(IMP-14) on a Plasmid Harboring Multiple Drug Resistance Genes in Escherichia coli Sequence Type 131 |
title_full_unstemmed | First Report of bla(IMP-14) on a Plasmid Harboring Multiple Drug Resistance Genes in Escherichia coli Sequence Type 131 |
title_short | First Report of bla(IMP-14) on a Plasmid Harboring Multiple Drug Resistance Genes in Escherichia coli Sequence Type 131 |
title_sort | first report of bla(imp-14) on a plasmid harboring multiple drug resistance genes in escherichia coli sequence type 131 |
topic | Epidemiology and Surveillance |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958194/ https://www.ncbi.nlm.nih.gov/pubmed/27246777 http://dx.doi.org/10.1128/AAC.00840-16 |
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