Mutations in the Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL) Confer Multidrug Resistance

Mutations in the Plasmodium falciparum cyclic amine resistance locus (PfCARL) are associated with parasite resistance to the imidazolopiperazines, a potent class of novel antimalarial compounds that display both prophylactic and transmission-blocking activity, in addition to activity against blood-s...

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Detalles Bibliográficos
Autores principales: LaMonte, Gregory, Lim, Michelle Yi-Xiu, Wree, Melanie, Reimer, Christin, Nachon, Marie, Corey, Victoria, Gedeck, Peter, Plouffe, David, Du, Alan, Figueroa, Nelissa, Yeung, Bryan, Bifani, Pablo, Winzeler, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958248/
https://www.ncbi.nlm.nih.gov/pubmed/27381290
http://dx.doi.org/10.1128/mBio.00696-16

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