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Effector Protein Cig2 Decreases Host Tolerance of Infection by Directing Constitutive Fusion of Autophagosomes with the Coxiella-Containing Vacuole

Coxiella burnetii replicates in an acidified lysosome-derived vacuole. Biogenesis of the Coxiella-containing vacuole (CCV) requires bacterial effector proteins delivered into host cells by the Dot/Icm secretion system. Genetic and cell biological analysis revealed that an effector protein called Cig...

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Detalles Bibliográficos
Autores principales:	Kohler, Lara J., Reed, Shawna R., Sarraf, Shireen A., Arteaga, David D., Newton, Hayley J., Roy, Craig R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958265/ https://www.ncbi.nlm.nih.gov/pubmed/27435465 http://dx.doi.org/10.1128/mBio.01127-16

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