Metabolite profile of a mouse model of Charcot–Marie–Tooth type 2D neuropathy: implications for disease mechanisms and interventions

Charcot–Marie–Tooth disease encompasses a genetically heterogeneous class of heritable polyneuropathies that result in axonal degeneration in the peripheral nervous system. Charcot–Marie–Tooth type 2D neuropathy (CMT2D) is caused by dominant mutations in glycyl tRNA synthetase (GARS). Mutations in t...

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Detalles Bibliográficos
Autores principales: Bais, Preeti, Beebe, Kirk, Morelli, Kathryn H., Currie, Meagan E., Norberg, Sara N., Evsikov, Alexei V., Miers, Kathy E., Seburn, Kevin L., Guergueltcheva, Velina, Kremensky, Ivo, Jordanova, Albena, Bult, Carol J., Burgess, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958279/
https://www.ncbi.nlm.nih.gov/pubmed/27288508
http://dx.doi.org/10.1242/bio.019273

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