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Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing

New hair follicles (HFs) do not form in adult mammalian skin unless epidermal Wnt signalling is activated genetically or within large wounds. To understand the postnatal loss of hair forming ability we monitored HF formation at small circular (2 mm) wound sites. At P2, new HFs formed in back skin, b...

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Detalles Bibliográficos
Autores principales: Rognoni, Emanuel, Gomez, Celine, Pisco, Angela Oliveira, Rawlins, Emma L., Simons, Ben D., Watt, Fiona M., Driskell, Ryan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958333/
https://www.ncbi.nlm.nih.gov/pubmed/27287810
http://dx.doi.org/10.1242/dev.131797