Cargando…

Endocannabinoid system as a regulator of tumor cell malignancy – biological pathways and clinical significance

The endocannabinoid system (ECS) comprises cannabinoid receptors (CBs), endogenous cannabinoids, and enzymes responsible for their synthesis, transport, and degradation of (endo)cannabinoids. To date, two CBs, CB1 and CB2, have been characterized; however, orphan G-protein-coupled receptor GPR55 has...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pyszniak, Maria, Tabarkiewicz, Jacek, Łuszczki, Jarogniew J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958360/ https://www.ncbi.nlm.nih.gov/pubmed/27486335 http://dx.doi.org/10.2147/OTT.S106944

Ejemplares similares

Percentages of NKT cells in the tissues of patients with non-small cell lung cancer who underwent surgical treatment
por: Pyszniak, Maria, et al.
Publicado: (2014)

Anticancer effect of terpenes: focus on malignant melanoma
por: Wróblewska-Łuczka, Paula, et al.
Publicado: (2023)

Synergy, Additivity and Antagonism between Esculetin and Six Commonly Used Chemotherapeutics in Various Malignant Melanoma Cell Lines—An Isobolographic Analysis
por: Wróblewska-Łuczka, Paula, et al.
Publicado: (2023)

The Clinical Significance of Endocannabinoids in Endometriosis Pain Management
por: Bouaziz, Jerome, et al.
Publicado: (2017)

The Interplay between Cancer Biology and the Endocannabinoid System—Significance for Cancer Risk, Prognosis and Response to Treatment
por: Moreno, Estefanía, et al.
Publicado: (2020)

Exploration of Multiverse Activities of Endocannabinoids in Biological Systems
por: Behl, Tapan, et al.
Publicado: (2022)

Endocannabinoid System: Chemical Characteristics and Biological Activity
por: Rezende, Bismarck, et al.
Publicado: (2023)

The Immune Endocannabinoid System of the Tumor Microenvironment
por: Kienzl, Melanie, et al.
Publicado: (2020)

N-Acetyl-L-cysteine Affects Ototoxicity Evoked by Amikacin and Furosemide Either Alone or in Combination in a Mouse Model of Hearing Threshold Decrease
por: Zadrożniak, Marek, et al.
Publicado: (2023)

Effects of WIN 55,212-2 (a non-selective cannabinoid CB(1) and CB(2) receptor agonist) on the protective action of various classical antiepileptic drugs in the mouse 6 Hz psychomotor seizure model
por: Florek-Luszczki, Magdalena, et al.
Publicado: (2014)

Clinical utility of adjunctive retigabine in partial onset seizures in adults
por: Rejdak, Konrad, et al.
Publicado: (2012)

Synergy, Additivity, and Antagonism between Cisplatin and Selected Coumarins in Human Melanoma Cells
por: Wróblewska-Łuczka, Paula, et al.
Publicado: (2021)

Additive Interactions between Betulinic Acid and Two Taxanes in In Vitro Tests against Four Human Malignant Melanoma Cell Lines
por: Wróblewska-Łuczka, Paula, et al.
Publicado: (2022)

Daphnetin, a Coumarin with Anticancer Potential against Human Melanoma: In Vitro Study of Its Effective Combination with Selected Cytostatic Drugs
por: Wróblewska-Łuczka, Paula, et al.
Publicado: (2023)

Dynamic regulation of the endocannabinoid system: implications for analgesia
por: Sagar, Devi Rani, et al.
Publicado: (2009)

Role of the Endocannabinoid System in the Regulation of Intestinal Homeostasis
por: Cuddihey, Hailey, et al.
Publicado: (2022)

Care and Feeding of the Endocannabinoid System: A Systematic Review of Potential Clinical Interventions that Upregulate the Endocannabinoid System
por: McPartland, John M., et al.
Publicado: (2014)

Effect of interleukin-6, -17, -21, -22, and -23 and STAT3 on signal transduction pathways and their inhibition in autoimmune arthritis
por: Woś, Izabela, et al.
Publicado: (2021)

Translating Endocannabinoid Biology into Clinical Practice: Cannabidiol for Stroke Prevention
por: Scharf, Eugene L.
Publicado: (2017)

Sub-additive (antagonistic) interaction of lacosamide with lamotrigine and valproate in the maximal electroshock-induced seizure model in mice: an isobolographic analysis
por: Łuszczki, Jarogniew J., et al.
Publicado: (2020)

Comparison of the Anticancer Effects of Arvanil and Olvanil When Combined with Cisplatin and Mitoxantrone in Various Melanoma Cell Lines—An Isobolographic Analysis
por: Marzęda, Paweł, et al.
Publicado: (2022)

Anticonvulsant effects of isopimpinellin and its interactions with classic antiseizure medications and borneol in the mouse tonic–clonic seizure model: an isobolographic transformation
por: Łuszczki, Jarogniew J., et al.
Publicado: (2023)

The endocannabinoid system: an overview
por: Battista, Natalia, et al.
Publicado: (2012)

The Endocannabinoid System and Spermatogenesis
por: Grimaldi, Paola, et al.
Publicado: (2013)

The Endocannabinoid System of Animals
por: Silver, Robert J.
Publicado: (2019)

Endocannabinoid System in the Airways
por: Bozkurt, Turgut Emrah
Publicado: (2019)

The Epigenetics of the Endocannabinoid System
por: Meccariello, Rosaria, et al.
Publicado: (2020)

The endocannabinoid system and breathing
por: Wiese, Beth M., et al.
Publicado: (2023)

The Endocannabinoid System as a Window Into Microglial Biology and Its Relationship to Autism
por: Araujo, Daniel John, et al.
Publicado: (2019)

The Endocannabinoid System Differentially Regulates Escape Behavior in Mice
por: Genewsky, Andreas J., et al.
Publicado: (2017)

Polygonogram and isobolographic analysis of interactions between various novel antiepileptic drugs in the 6-Hz corneal stimulation-induced seizure model in mice
por: Luszczki, Jarogniew J., et al.
Publicado: (2020)

Cannabidiol Interacts Antagonistically with Cisplatin and Additively with Mitoxantrone in Various Melanoma Cell Lines—An Isobolographic Analysis
por: Marzęda, Paweł, et al.
Publicado: (2022)

Cannabinoids and their derivatives in struggle against melanoma
por: Marzęda, Paweł, et al.
Publicado: (2021)

Assessment of Pharmacological Interactions between SIRT2 Inhibitor AGK2 and Paclitaxel in Different Molecular Subtypes of Breast Cancer Cells
por: Wawruszak, Anna, et al.
Publicado: (2022)

Antagonistic Pharmacological Interaction between Sirtuin Inhibitor Cambinol and Paclitaxel in Triple-Negative Breast Cancer Cell Lines: An Isobolographic Analysis
por: Wawruszak, Anna, et al.
Publicado: (2022)

Additive pharmacological interaction between sirtuin inhibitor cambinol and paclitaxel in MCF7 luminal and MDA-MB-231 triple-negative breast cancer cells
por: Wawruszak, Anna, et al.
Publicado: (2022)

Antiseizure Effects of Scoparone, Borneol and Their Impact on the Anticonvulsant Potency of Four Classic Antiseizure Medications in the Mouse MES Model—An Isobolographic Transformation
por: Łuszczki, Jarogniew J., et al.
Publicado: (2023)

Regulatory T lymphocytes and transforming growth factor beta in epithelial ovarian tumors-prognostic significance
por: Winkler, Izabela, et al.
Publicado: (2015)

Influence of dronedarone (a class III antiarrhythmic drug) on the anticonvulsant potency of four classical antiepileptic drugs in the tonic–clonic seizure model in mice
por: Sawicka, Katarzyna M., et al.
Publicado: (2018)

The Endocannabinoid System and PPARs: Focus on Their Signalling Crosstalk, Action and Transcriptional Regulation
por: Iannotti, Fabio Arturo, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7tmn1rm9559bb3ojam2lh6rlic