Paliperidone Induced Hypoglycemia by Increasing Insulin Secretion

We report the case of a 41-year-old woman with schizophrenia who developed persistent hypoglycemia following paliperidone administration. After discontinuing paliperidone, the hypoglycemia resolved, but symptoms of diabetes emerged. Therefore, it appears that the hypoglycemia induced by paliperidone...

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Detalles Bibliográficos
Autores principales: Omi, Tsubasa, Riku, Keisen, Fukumoto, Motoyuki, Kanai, Koji, Omura, Yumi, Takada, Hiromune, Matunaga, Hidenori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958443/
https://www.ncbi.nlm.nih.gov/pubmed/27478670
http://dx.doi.org/10.1155/2016/1805414
Descripción
Sumario:We report the case of a 41-year-old woman with schizophrenia who developed persistent hypoglycemia following paliperidone administration. After discontinuing paliperidone, the hypoglycemia resolved, but symptoms of diabetes emerged. Therefore, it appears that the hypoglycemia induced by paliperidone may mask symptoms of diabetes. Paliperidone may induce hypoglycemia by increasing insulin secretion. This report could help elucidate the relationship between atypical antipsychotics and glucose metabolism.

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