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Paliperidone Induced Hypoglycemia by Increasing Insulin Secretion

We report the case of a 41-year-old woman with schizophrenia who developed persistent hypoglycemia following paliperidone administration. After discontinuing paliperidone, the hypoglycemia resolved, but symptoms of diabetes emerged. Therefore, it appears that the hypoglycemia induced by paliperidone...

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Detalles Bibliográficos
Autores principales: Omi, Tsubasa, Riku, Keisen, Fukumoto, Motoyuki, Kanai, Koji, Omura, Yumi, Takada, Hiromune, Matunaga, Hidenori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958443/
https://www.ncbi.nlm.nih.gov/pubmed/27478670
http://dx.doi.org/10.1155/2016/1805414
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author Omi, Tsubasa
Riku, Keisen
Fukumoto, Motoyuki
Kanai, Koji
Omura, Yumi
Takada, Hiromune
Matunaga, Hidenori
author_facet Omi, Tsubasa
Riku, Keisen
Fukumoto, Motoyuki
Kanai, Koji
Omura, Yumi
Takada, Hiromune
Matunaga, Hidenori
author_sort Omi, Tsubasa
collection PubMed
description We report the case of a 41-year-old woman with schizophrenia who developed persistent hypoglycemia following paliperidone administration. After discontinuing paliperidone, the hypoglycemia resolved, but symptoms of diabetes emerged. Therefore, it appears that the hypoglycemia induced by paliperidone may mask symptoms of diabetes. Paliperidone may induce hypoglycemia by increasing insulin secretion. This report could help elucidate the relationship between atypical antipsychotics and glucose metabolism.
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spelling pubmed-49584432016-07-31 Paliperidone Induced Hypoglycemia by Increasing Insulin Secretion Omi, Tsubasa Riku, Keisen Fukumoto, Motoyuki Kanai, Koji Omura, Yumi Takada, Hiromune Matunaga, Hidenori Case Rep Psychiatry Case Report We report the case of a 41-year-old woman with schizophrenia who developed persistent hypoglycemia following paliperidone administration. After discontinuing paliperidone, the hypoglycemia resolved, but symptoms of diabetes emerged. Therefore, it appears that the hypoglycemia induced by paliperidone may mask symptoms of diabetes. Paliperidone may induce hypoglycemia by increasing insulin secretion. This report could help elucidate the relationship between atypical antipsychotics and glucose metabolism. Hindawi Publishing Corporation 2016 2016-07-10 /pmc/articles/PMC4958443/ /pubmed/27478670 http://dx.doi.org/10.1155/2016/1805414 Text en Copyright © 2016 Tsubasa Omi et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Omi, Tsubasa
Riku, Keisen
Fukumoto, Motoyuki
Kanai, Koji
Omura, Yumi
Takada, Hiromune
Matunaga, Hidenori
Paliperidone Induced Hypoglycemia by Increasing Insulin Secretion
title Paliperidone Induced Hypoglycemia by Increasing Insulin Secretion
title_full Paliperidone Induced Hypoglycemia by Increasing Insulin Secretion
title_fullStr Paliperidone Induced Hypoglycemia by Increasing Insulin Secretion
title_full_unstemmed Paliperidone Induced Hypoglycemia by Increasing Insulin Secretion
title_short Paliperidone Induced Hypoglycemia by Increasing Insulin Secretion
title_sort paliperidone induced hypoglycemia by increasing insulin secretion
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958443/
https://www.ncbi.nlm.nih.gov/pubmed/27478670
http://dx.doi.org/10.1155/2016/1805414
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