Two Cases of Legionella pneumophila Pneumonia with Prolonged Neurologic Symptoms and Brain Hypoperfusion on Single-Photon Emission Computed Tomography

Cerebral and cerebellar symptoms are frequently associated with Legionnaires' disease. However, corresponding brain lesions are difficult to demonstrate using either computed tomography (CT) or magnetic resonance imaging (MRI). We report here two patients with Legionella pneumophila pneumonia a...

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Autores principales: Ohta, Hiromitsu, Yamazaki, Susumu, Miura, You, Seto, Akira, Kanazawa, Minoru, Nagata, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958445/
https://www.ncbi.nlm.nih.gov/pubmed/27478660
http://dx.doi.org/10.1155/2016/5264681
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author Ohta, Hiromitsu
Yamazaki, Susumu
Miura, You
Seto, Akira
Kanazawa, Minoru
Nagata, Makoto
author_facet Ohta, Hiromitsu
Yamazaki, Susumu
Miura, You
Seto, Akira
Kanazawa, Minoru
Nagata, Makoto
author_sort Ohta, Hiromitsu
collection PubMed
description Cerebral and cerebellar symptoms are frequently associated with Legionnaires' disease. However, corresponding brain lesions are difficult to demonstrate using either computed tomography (CT) or magnetic resonance imaging (MRI). We report here two patients with Legionella pneumophila pneumonia accompanied by prolonged neurologic symptoms. In contrast to brain CT and MRI, which failed to detect any abnormalities, single-photon emission computed tomography (SPECT) showed multiple sites of hypoperfusion within the brains of both patients. These cases suggest that vasculopathy, which is detectable by SPECT, might be one of the causes of neurologic symptoms in patients with Legionnaires' disease.
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spelling pubmed-49584452016-07-31 Two Cases of Legionella pneumophila Pneumonia with Prolonged Neurologic Symptoms and Brain Hypoperfusion on Single-Photon Emission Computed Tomography Ohta, Hiromitsu Yamazaki, Susumu Miura, You Seto, Akira Kanazawa, Minoru Nagata, Makoto Case Rep Infect Dis Case Report Cerebral and cerebellar symptoms are frequently associated with Legionnaires' disease. However, corresponding brain lesions are difficult to demonstrate using either computed tomography (CT) or magnetic resonance imaging (MRI). We report here two patients with Legionella pneumophila pneumonia accompanied by prolonged neurologic symptoms. In contrast to brain CT and MRI, which failed to detect any abnormalities, single-photon emission computed tomography (SPECT) showed multiple sites of hypoperfusion within the brains of both patients. These cases suggest that vasculopathy, which is detectable by SPECT, might be one of the causes of neurologic symptoms in patients with Legionnaires' disease. Hindawi Publishing Corporation 2016 2016-07-10 /pmc/articles/PMC4958445/ /pubmed/27478660 http://dx.doi.org/10.1155/2016/5264681 Text en Copyright © 2016 Hiromitsu Ohta et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ohta, Hiromitsu
Yamazaki, Susumu
Miura, You
Seto, Akira
Kanazawa, Minoru
Nagata, Makoto
Two Cases of Legionella pneumophila Pneumonia with Prolonged Neurologic Symptoms and Brain Hypoperfusion on Single-Photon Emission Computed Tomography
title Two Cases of Legionella pneumophila Pneumonia with Prolonged Neurologic Symptoms and Brain Hypoperfusion on Single-Photon Emission Computed Tomography
title_full Two Cases of Legionella pneumophila Pneumonia with Prolonged Neurologic Symptoms and Brain Hypoperfusion on Single-Photon Emission Computed Tomography
title_fullStr Two Cases of Legionella pneumophila Pneumonia with Prolonged Neurologic Symptoms and Brain Hypoperfusion on Single-Photon Emission Computed Tomography
title_full_unstemmed Two Cases of Legionella pneumophila Pneumonia with Prolonged Neurologic Symptoms and Brain Hypoperfusion on Single-Photon Emission Computed Tomography
title_short Two Cases of Legionella pneumophila Pneumonia with Prolonged Neurologic Symptoms and Brain Hypoperfusion on Single-Photon Emission Computed Tomography
title_sort two cases of legionella pneumophila pneumonia with prolonged neurologic symptoms and brain hypoperfusion on single-photon emission computed tomography
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958445/
https://www.ncbi.nlm.nih.gov/pubmed/27478660
http://dx.doi.org/10.1155/2016/5264681
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