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An Ultrasound Simulation Model for the Pulsatile Blood Flow Modulated by the Motion of Stenosed Vessel Wall

This paper presents an ultrasound simulation model for pulsatile blood flow, modulated by the motion of a stenosed vessel wall. It aims at generating more realistic ultrasonic signals to provide an environment for evaluating ultrasound signal processing and imaging and a framework for investigating...

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Detalles Bibliográficos
Autores principales: Zhang, Qinghui, Zhang, Yufeng, Zhou, Yi, Zhang, Kun, Zhang, Kexin, Gao, Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958452/
https://www.ncbi.nlm.nih.gov/pubmed/27478840
http://dx.doi.org/10.1155/2016/8502873
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author Zhang, Qinghui
Zhang, Yufeng
Zhou, Yi
Zhang, Kun
Zhang, Kexin
Gao, Lian
author_facet Zhang, Qinghui
Zhang, Yufeng
Zhou, Yi
Zhang, Kun
Zhang, Kexin
Gao, Lian
author_sort Zhang, Qinghui
collection PubMed
description This paper presents an ultrasound simulation model for pulsatile blood flow, modulated by the motion of a stenosed vessel wall. It aims at generating more realistic ultrasonic signals to provide an environment for evaluating ultrasound signal processing and imaging and a framework for investigating the behaviors of blood flow field modulated by wall motion. This model takes into account fluid-structure interaction, blood pulsatility, stenosis of the vessel, and arterial wall movement caused by surrounding tissue's motion. The axial and radial velocity distributions of blood and the displacement of vessel wall are calculated by solving coupled Navier-Stokes and wall equations. With these obtained values, we made several different phantoms by treating blood and the vessel wall as a group of point scatterers. Then, ultrasound echoed signals from oscillating wall and blood in the axisymmetric stenotic-carotid arteries were computed by ultrasound simulation software, Field II. The results show better consistency with corresponding theoretical values and clinical data and reflect the influence of wall movement on the flow field. It can serve as an effective tool not only for investigating the behavior of blood flow field modulated by wall motion but also for quantitative or qualitative evaluation of new ultrasound imaging technology and estimation method of blood velocity.
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spelling pubmed-49584522016-07-31 An Ultrasound Simulation Model for the Pulsatile Blood Flow Modulated by the Motion of Stenosed Vessel Wall Zhang, Qinghui Zhang, Yufeng Zhou, Yi Zhang, Kun Zhang, Kexin Gao, Lian Biomed Res Int Research Article This paper presents an ultrasound simulation model for pulsatile blood flow, modulated by the motion of a stenosed vessel wall. It aims at generating more realistic ultrasonic signals to provide an environment for evaluating ultrasound signal processing and imaging and a framework for investigating the behaviors of blood flow field modulated by wall motion. This model takes into account fluid-structure interaction, blood pulsatility, stenosis of the vessel, and arterial wall movement caused by surrounding tissue's motion. The axial and radial velocity distributions of blood and the displacement of vessel wall are calculated by solving coupled Navier-Stokes and wall equations. With these obtained values, we made several different phantoms by treating blood and the vessel wall as a group of point scatterers. Then, ultrasound echoed signals from oscillating wall and blood in the axisymmetric stenotic-carotid arteries were computed by ultrasound simulation software, Field II. The results show better consistency with corresponding theoretical values and clinical data and reflect the influence of wall movement on the flow field. It can serve as an effective tool not only for investigating the behavior of blood flow field modulated by wall motion but also for quantitative or qualitative evaluation of new ultrasound imaging technology and estimation method of blood velocity. Hindawi Publishing Corporation 2016 2016-07-10 /pmc/articles/PMC4958452/ /pubmed/27478840 http://dx.doi.org/10.1155/2016/8502873 Text en Copyright © 2016 Qinghui Zhang et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zhang, Qinghui
Zhang, Yufeng
Zhou, Yi
Zhang, Kun
Zhang, Kexin
Gao, Lian
An Ultrasound Simulation Model for the Pulsatile Blood Flow Modulated by the Motion of Stenosed Vessel Wall
title An Ultrasound Simulation Model for the Pulsatile Blood Flow Modulated by the Motion of Stenosed Vessel Wall
title_full An Ultrasound Simulation Model for the Pulsatile Blood Flow Modulated by the Motion of Stenosed Vessel Wall
title_fullStr An Ultrasound Simulation Model for the Pulsatile Blood Flow Modulated by the Motion of Stenosed Vessel Wall
title_full_unstemmed An Ultrasound Simulation Model for the Pulsatile Blood Flow Modulated by the Motion of Stenosed Vessel Wall
title_short An Ultrasound Simulation Model for the Pulsatile Blood Flow Modulated by the Motion of Stenosed Vessel Wall
title_sort ultrasound simulation model for the pulsatile blood flow modulated by the motion of stenosed vessel wall
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958452/
https://www.ncbi.nlm.nih.gov/pubmed/27478840
http://dx.doi.org/10.1155/2016/8502873
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