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Increased MMP‐7 expression in biliary epithelium and serum underpins native liver fibrosis after successful portoenterostomy in biliary atresia

The molecular mechanisms underlying progressive liver fibrosis following surgical treatment of biliary atresia (BA) remain unclear. Our aim was to address hepatic gene and protein expression and serum levels of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) after successful por...

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Detalles Bibliográficos
Autores principales: Kerola, Anna, Lampela, Hanna, Lohi, Jouko, Heikkilä, Päivi, Mutanen, Annika, Hagström, Jaana, Tervahartiala, Taina, Sorsa, Timo, Haglund, Caj, Jalanko, Hannu, Pakarinen, Mikko P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958739/
https://www.ncbi.nlm.nih.gov/pubmed/27499927
http://dx.doi.org/10.1002/cjp2.50