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Aldehyde dehydrogenase 2 is associated with cognitive functions in patients with Parkinson’s disease

Neurotransmitter degradation has been proposed to cause the accumulation of neurotoxic metabolites. The metabolism of these metabolites involves aldehyde dehydrogenase 2 (ALDH2). The Asian-specific single nucleotide polymorphism rs671 causes reduced enzyme activity. This study aims to explore whethe...

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Detalles Bibliográficos
Autores principales: Yu, Rwei-Ling, Tan, Chun-Hsiang, Lu, Ying-Che, Wu, Ruey-Meei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958972/
https://www.ncbi.nlm.nih.gov/pubmed/27453488
http://dx.doi.org/10.1038/srep30424