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Revisiting the mechanism of coagulation factor XIII activation and regulation from a structure/functional perspective

The activation and regulation of coagulation Factor XIII (FXIII) protein has been the subject of active research for the past three decades. Although discrete evidence exists on various aspects of FXIII activation and regulation a combinatorial structure/functional view in this regard is lacking. In...

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Detalles Bibliográficos
Autores principales: Gupta, Sneha, Biswas, Arijit, Akhter, Mohammad Suhail, Krettler, Christoph, Reinhart, Christoph, Dodt, Johannes, Reuter, Andreas, Philippou, Helen, Ivaskevicius, Vytautas, Oldenburg, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958977/
https://www.ncbi.nlm.nih.gov/pubmed/27453290
http://dx.doi.org/10.1038/srep30105