Gastrokine 1 mRNA in human sera is not informative biomarker for gastric cancer

BACKGROUND: We aimed to ascertain if Gastrokine 1 mRNA in the sera of patients with gastric cancer might be an informative biomarker for the disease. RESULTS: Analysis of GKN1 mRNA in serum samples from healthy individuals (n = 23) and from patients with diagnosis of gastric cancer (n = 16), perform...

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Detalles Bibliográficos
Autores principales: Villano, Valentina, Di Stadio, Chiara Stella, Federico, Antonella, Altieri, Filomena, Miselli, Giuseppina, De Palma, Maurizio, Rippa, Emilia, Arcari, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959057/
https://www.ncbi.nlm.nih.gov/pubmed/27452910
http://dx.doi.org/10.1186/s12952-016-0057-9
Descripción
Sumario:BACKGROUND: We aimed to ascertain if Gastrokine 1 mRNA in the sera of patients with gastric cancer might be an informative biomarker for the disease. RESULTS: Analysis of GKN1 mRNA in serum samples from healthy individuals (n = 23) and from patients with diagnosis of gastric cancer (n = 16), performed by using absolute quantification based on standard curve method, did not show any significative statistical difference between the two unpaired group of individuals. CONCLUSIONS: Our preliminary results did not confirm GKN1 as a potential biomarker for gastric cancer.

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