Gastrokine 1 mRNA in human sera is not informative biomarker for gastric cancer

BACKGROUND: We aimed to ascertain if Gastrokine 1 mRNA in the sera of patients with gastric cancer might be an informative biomarker for the disease. RESULTS: Analysis of GKN1 mRNA in serum samples from healthy individuals (n = 23) and from patients with diagnosis of gastric cancer (n = 16), perform...

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Autores principales: Villano, Valentina, Di Stadio, Chiara Stella, Federico, Antonella, Altieri, Filomena, Miselli, Giuseppina, De Palma, Maurizio, Rippa, Emilia, Arcari, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959057/
https://www.ncbi.nlm.nih.gov/pubmed/27452910
http://dx.doi.org/10.1186/s12952-016-0057-9
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author Villano, Valentina
Di Stadio, Chiara Stella
Federico, Antonella
Altieri, Filomena
Miselli, Giuseppina
De Palma, Maurizio
Rippa, Emilia
Arcari, Paolo
author_facet Villano, Valentina
Di Stadio, Chiara Stella
Federico, Antonella
Altieri, Filomena
Miselli, Giuseppina
De Palma, Maurizio
Rippa, Emilia
Arcari, Paolo
author_sort Villano, Valentina
collection PubMed
description BACKGROUND: We aimed to ascertain if Gastrokine 1 mRNA in the sera of patients with gastric cancer might be an informative biomarker for the disease. RESULTS: Analysis of GKN1 mRNA in serum samples from healthy individuals (n = 23) and from patients with diagnosis of gastric cancer (n = 16), performed by using absolute quantification based on standard curve method, did not show any significative statistical difference between the two unpaired group of individuals. CONCLUSIONS: Our preliminary results did not confirm GKN1 as a potential biomarker for gastric cancer.
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spelling pubmed-49590572016-07-26 Gastrokine 1 mRNA in human sera is not informative biomarker for gastric cancer Villano, Valentina Di Stadio, Chiara Stella Federico, Antonella Altieri, Filomena Miselli, Giuseppina De Palma, Maurizio Rippa, Emilia Arcari, Paolo J Negat Results Biomed Brief Report BACKGROUND: We aimed to ascertain if Gastrokine 1 mRNA in the sera of patients with gastric cancer might be an informative biomarker for the disease. RESULTS: Analysis of GKN1 mRNA in serum samples from healthy individuals (n = 23) and from patients with diagnosis of gastric cancer (n = 16), performed by using absolute quantification based on standard curve method, did not show any significative statistical difference between the two unpaired group of individuals. CONCLUSIONS: Our preliminary results did not confirm GKN1 as a potential biomarker for gastric cancer. BioMed Central 2016-07-25 /pmc/articles/PMC4959057/ /pubmed/27452910 http://dx.doi.org/10.1186/s12952-016-0057-9 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Brief Report
Villano, Valentina
Di Stadio, Chiara Stella
Federico, Antonella
Altieri, Filomena
Miselli, Giuseppina
De Palma, Maurizio
Rippa, Emilia
Arcari, Paolo
Gastrokine 1 mRNA in human sera is not informative biomarker for gastric cancer
title Gastrokine 1 mRNA in human sera is not informative biomarker for gastric cancer
title_full Gastrokine 1 mRNA in human sera is not informative biomarker for gastric cancer
title_fullStr Gastrokine 1 mRNA in human sera is not informative biomarker for gastric cancer
title_full_unstemmed Gastrokine 1 mRNA in human sera is not informative biomarker for gastric cancer
title_short Gastrokine 1 mRNA in human sera is not informative biomarker for gastric cancer
title_sort gastrokine 1 mrna in human sera is not informative biomarker for gastric cancer
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959057/
https://www.ncbi.nlm.nih.gov/pubmed/27452910
http://dx.doi.org/10.1186/s12952-016-0057-9
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