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Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi‐walled carbon nanotubes

Despite concerns over toxicity, carbon nanotubes have been extensively investigated for potential applications in nanomedicine because of their small size, unique properties, and ability to carry cargo such as small molecules and nucleic acids. Herein, we show that polymer nanotubes can be synthesiz...

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Detalles Bibliográficos
Autores principales: Newland, Ben, Thomas, Laurent, Zheng, Yu, Steinhart, Martin, Werner, Carsten, Wang, Wenxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959090/
https://www.ncbi.nlm.nih.gov/pubmed/27512602
http://dx.doi.org/10.1002/jin2.7
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author Newland, Ben
Thomas, Laurent
Zheng, Yu
Steinhart, Martin
Werner, Carsten
Wang, Wenxin
author_facet Newland, Ben
Thomas, Laurent
Zheng, Yu
Steinhart, Martin
Werner, Carsten
Wang, Wenxin
author_sort Newland, Ben
collection PubMed
description Despite concerns over toxicity, carbon nanotubes have been extensively investigated for potential applications in nanomedicine because of their small size, unique properties, and ability to carry cargo such as small molecules and nucleic acids. Herein, we show that polymer nanotubes can be synthesized quickly and easily from a homopolymer of ethylene glycol dimethacrylate (EGDMA). The nanotubes formed via photo‐initiated polymerization of the highly functional prepolymer, inside an anodized aluminium oxide template, have a regular structure and large internal pore and can be loaded with a fluorescent dye within minutes representing a simple alternative to multi‐walled carbon nanotubes for biomedical applications.
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spelling pubmed-49590902016-08-08 Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi‐walled carbon nanotubes Newland, Ben Thomas, Laurent Zheng, Yu Steinhart, Martin Werner, Carsten Wang, Wenxin J Interdiscip Nanomed Original Articles Despite concerns over toxicity, carbon nanotubes have been extensively investigated for potential applications in nanomedicine because of their small size, unique properties, and ability to carry cargo such as small molecules and nucleic acids. Herein, we show that polymer nanotubes can be synthesized quickly and easily from a homopolymer of ethylene glycol dimethacrylate (EGDMA). The nanotubes formed via photo‐initiated polymerization of the highly functional prepolymer, inside an anodized aluminium oxide template, have a regular structure and large internal pore and can be loaded with a fluorescent dye within minutes representing a simple alternative to multi‐walled carbon nanotubes for biomedical applications. John Wiley and Sons Inc. 2016-04-21 2016-04 /pmc/articles/PMC4959090/ /pubmed/27512602 http://dx.doi.org/10.1002/jin2.7 Text en © 2016 The Authors. Journal of Interdisciplinary Nanomedicine published by John Wiley & Sons Ltd and the British Society for Nanomedicine. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Newland, Ben
Thomas, Laurent
Zheng, Yu
Steinhart, Martin
Werner, Carsten
Wang, Wenxin
Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi‐walled carbon nanotubes
title Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi‐walled carbon nanotubes
title_full Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi‐walled carbon nanotubes
title_fullStr Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi‐walled carbon nanotubes
title_full_unstemmed Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi‐walled carbon nanotubes
title_short Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi‐walled carbon nanotubes
title_sort preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi‐walled carbon nanotubes
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959090/
https://www.ncbi.nlm.nih.gov/pubmed/27512602
http://dx.doi.org/10.1002/jin2.7
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