Cargando…
Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi‐walled carbon nanotubes
Despite concerns over toxicity, carbon nanotubes have been extensively investigated for potential applications in nanomedicine because of their small size, unique properties, and ability to carry cargo such as small molecules and nucleic acids. Herein, we show that polymer nanotubes can be synthesiz...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959090/ https://www.ncbi.nlm.nih.gov/pubmed/27512602 http://dx.doi.org/10.1002/jin2.7 |
_version_ | 1782444365780615168 |
---|---|
author | Newland, Ben Thomas, Laurent Zheng, Yu Steinhart, Martin Werner, Carsten Wang, Wenxin |
author_facet | Newland, Ben Thomas, Laurent Zheng, Yu Steinhart, Martin Werner, Carsten Wang, Wenxin |
author_sort | Newland, Ben |
collection | PubMed |
description | Despite concerns over toxicity, carbon nanotubes have been extensively investigated for potential applications in nanomedicine because of their small size, unique properties, and ability to carry cargo such as small molecules and nucleic acids. Herein, we show that polymer nanotubes can be synthesized quickly and easily from a homopolymer of ethylene glycol dimethacrylate (EGDMA). The nanotubes formed via photo‐initiated polymerization of the highly functional prepolymer, inside an anodized aluminium oxide template, have a regular structure and large internal pore and can be loaded with a fluorescent dye within minutes representing a simple alternative to multi‐walled carbon nanotubes for biomedical applications. |
format | Online Article Text |
id | pubmed-4959090 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-49590902016-08-08 Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi‐walled carbon nanotubes Newland, Ben Thomas, Laurent Zheng, Yu Steinhart, Martin Werner, Carsten Wang, Wenxin J Interdiscip Nanomed Original Articles Despite concerns over toxicity, carbon nanotubes have been extensively investigated for potential applications in nanomedicine because of their small size, unique properties, and ability to carry cargo such as small molecules and nucleic acids. Herein, we show that polymer nanotubes can be synthesized quickly and easily from a homopolymer of ethylene glycol dimethacrylate (EGDMA). The nanotubes formed via photo‐initiated polymerization of the highly functional prepolymer, inside an anodized aluminium oxide template, have a regular structure and large internal pore and can be loaded with a fluorescent dye within minutes representing a simple alternative to multi‐walled carbon nanotubes for biomedical applications. John Wiley and Sons Inc. 2016-04-21 2016-04 /pmc/articles/PMC4959090/ /pubmed/27512602 http://dx.doi.org/10.1002/jin2.7 Text en © 2016 The Authors. Journal of Interdisciplinary Nanomedicine published by John Wiley & Sons Ltd and the British Society for Nanomedicine. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Newland, Ben Thomas, Laurent Zheng, Yu Steinhart, Martin Werner, Carsten Wang, Wenxin Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi‐walled carbon nanotubes |
title | Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi‐walled carbon nanotubes |
title_full | Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi‐walled carbon nanotubes |
title_fullStr | Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi‐walled carbon nanotubes |
title_full_unstemmed | Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi‐walled carbon nanotubes |
title_short | Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi‐walled carbon nanotubes |
title_sort | preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi‐walled carbon nanotubes |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959090/ https://www.ncbi.nlm.nih.gov/pubmed/27512602 http://dx.doi.org/10.1002/jin2.7 |
work_keys_str_mv | AT newlandben preparationloadingandcytotoxicityanalysisofpolymernanotubesfromanethyleneglycoldimethacrylatehomopolymerincomparisontomultiwalledcarbonnanotubes AT thomaslaurent preparationloadingandcytotoxicityanalysisofpolymernanotubesfromanethyleneglycoldimethacrylatehomopolymerincomparisontomultiwalledcarbonnanotubes AT zhengyu preparationloadingandcytotoxicityanalysisofpolymernanotubesfromanethyleneglycoldimethacrylatehomopolymerincomparisontomultiwalledcarbonnanotubes AT steinhartmartin preparationloadingandcytotoxicityanalysisofpolymernanotubesfromanethyleneglycoldimethacrylatehomopolymerincomparisontomultiwalledcarbonnanotubes AT wernercarsten preparationloadingandcytotoxicityanalysisofpolymernanotubesfromanethyleneglycoldimethacrylatehomopolymerincomparisontomultiwalledcarbonnanotubes AT wangwenxin preparationloadingandcytotoxicityanalysisofpolymernanotubesfromanethyleneglycoldimethacrylatehomopolymerincomparisontomultiwalledcarbonnanotubes |