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A Standardized Chemically Modified Curcuma longa Extract Modulates IRAK-MAPK Signaling in Inflammation and Potentiates Cytotoxicity

The TLR/IL-1R pathway is a critical signaling module that is misregulated in pathologies like inflammation and cancer. Extracts from turmeric (Curcuma longa L.) enriched in curcumin and carbonyls like turmerones have been shown to exert potent anti-inflammatory effects. The present study evaluated t...

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Detalles Bibliográficos
Autores principales: Rana, Minakshi, Maurya, Preeti, Reddy, Sukka S., Singh, Vishal, Ahmad, Hafsa, Dwivedi, Anil K., Dikshit, Madhu, Barthwal, Manoj K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959270/
https://www.ncbi.nlm.nih.gov/pubmed/27504095
http://dx.doi.org/10.3389/fphar.2016.00223