Cargando…
Dissecting protein architecture with communication blocks and communicating segment pairs
BACKGROUND: Proteins adapt to environmental conditions by changing their shape and motions. Characterising protein conformational dynamics is increasingly recognised as necessary to understand how proteins function. Given a conformational ensemble, computational tools are needed to extract in a syst...
Autores principales: | Karami, Yasaman, Laine, Elodie, Carbone, Alessandra |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959365/ https://www.ncbi.nlm.nih.gov/pubmed/26823083 http://dx.doi.org/10.1186/s12859-015-0855-y |
Ejemplares similares
-
GEMME: A Simple and Fast Global Epistatic Model Predicting Mutational Effects
por: Laine, Elodie, et al.
Publicado: (2019) -
“Infostery” analysis of short molecular dynamics simulations identifies highly sensitive residues and predicts deleterious mutations
por: Karami, Yasaman, et al.
Publicado: (2018) -
Predicting substitutions to modulate disorder and stability in coiled-coils
por: Karami, Yasaman, et al.
Publicado: (2020) -
Local Geometry and Evolutionary Conservation of Protein Surfaces Reveal the Multiple Recognition Patches in Protein-Protein Interactions
por: Laine, Elodie, et al.
Publicado: (2015) -
Allosteric Communication across the Native and Mutated KIT Receptor Tyrosine Kinase
por: Laine, Elodie, et al.
Publicado: (2012)