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MK-2206 co-treatment with 5-fluorouracil or doxorubicin enhances chemosensitivity and apoptosis in gastric cancer by attenuation of Akt phosphorylation

The anticancer effect of MK-2206, an Akt inhibitor, has been explored in some types of cancers, but its effect on gastric cancer is unclear. In this study, we aimed to investigate its anticancer effect in gastric cancer cells. Cell viability and colony formation assays showed that MK-2206 effectivel...

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Detalles Bibliográficos
Autores principales:	Jin, Piaopiao, Wong, Chi Chun, Mei, Sibin, He, Xingkang, Qian, Yun, Sun, Leimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959411/ https://www.ncbi.nlm.nih.gov/pubmed/27499633 http://dx.doi.org/10.2147/OTT.S106303

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