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Evaluation of Antihemagglutinin and Antineuraminidase Antibodies as Correlates of Protection in an Influenza A/H1N1 Virus Healthy Human Challenge Model

Despite long-term investment, influenza continues to be a significant worldwide problem. The cornerstone of protection remains vaccination, and approved vaccines seek to elicit a hemagglutination inhibition (HAI) titer of ≥1:40 as the primary correlate of protection. However, recent poor vaccine per...

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Detalles Bibliográficos
Autores principales: Memoli, Matthew J., Shaw, Pamela A., Han, Alison, Czajkowski, Lindsay, Reed, Susan, Athota, Rani, Bristol, Tyler, Fargis, Sarah, Risos, Kyle, Powers, John H., Davey, Richard T., Taubenberger, Jeffery K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959521/
https://www.ncbi.nlm.nih.gov/pubmed/27094330
http://dx.doi.org/10.1128/mBio.00417-16