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The Type I Interferon Response Determines Differences in Choroid Plexus Susceptibility between Newborns and Adults in Herpes Simplex Virus Encephalitis

Newborns are significantly more susceptible to severe viral encephalitis than adults, with differences in the host response to infection implicated as a major factor. However, the specific host signaling pathways responsible for differences in susceptibility and neurologic morbidity have remained un...

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Detalles Bibliográficos
Autores principales: Wilcox, Douglas R., Folmsbee, Stephen S., Muller, William J., Longnecker, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959527/
https://www.ncbi.nlm.nih.gov/pubmed/27073094
http://dx.doi.org/10.1128/mBio.00437-16

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