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Dual Transcriptome Profiling of Leishmania-Infected Human Macrophages Reveals Distinct Reprogramming Signatures

Macrophages are mononuclear phagocytes that constitute a first line of defense against pathogens. While lethal to many microbes, they are the primary host cells of Leishmania spp. parasites, the obligate intracellular pathogens that cause leishmaniasis. We conducted transcriptomic profiling of two L...

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Detalles Bibliográficos
Autores principales: Fernandes, Maria Cecilia, Dillon, Laura A. L., Belew, Ashton Trey, Bravo, Hector Corrada, Mosser, David M., El-Sayed, Najib M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959658/
https://www.ncbi.nlm.nih.gov/pubmed/27165796
http://dx.doi.org/10.1128/mBio.00027-16