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Differential Type I Interferon Signaling Is a Master Regulator of Susceptibility to Postinfluenza Bacterial Superinfection
Bacterial superinfections are a primary cause of death during influenza pandemics and epidemics. Type I interferon (IFN) signaling contributes to increased susceptibility of mice to bacterial superinfection around day 7 post-influenza A virus (IAV) infection. Here we demonstrate that the reduced sus...
Autores principales: | Shepardson, Kelly M., Larson, Kyle, Morton, Rachelle V., Prigge, Justin R., Schmidt, Edward E., Huber, Victor C., Rynda-Apple, Agnieszka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959663/ https://www.ncbi.nlm.nih.gov/pubmed/27143388 http://dx.doi.org/10.1128/mBio.00506-16 |
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