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Programming Native CRISPR Arrays for the Generation of Targeted Immunity
The adaptive immune system of prokaryotes, called CRISPR-Cas (clustered regularly interspaced short palindromic repeats and CRISPR-associated genes), results in specific cleavage of invading nucleic acid sequences recognized by the cell’s “memory” of past encounters. Here, we exploited the propertie...
Autores principales: | Hynes, Alexander P., Labrie, Simon J., Moineau, Sylvain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959665/ https://www.ncbi.nlm.nih.gov/pubmed/27143383 http://dx.doi.org/10.1128/mBio.00202-16 |
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