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Plasmodium falciparum Histidine-Rich Protein II Compromises Brain Endothelial Barriers and May Promote Cerebral Malaria Pathogenesis

Cerebral malaria (CM) is a disease of the vascular endothelium caused by Plasmodium falciparum. It is characterized by parasite sequestration, inflammatory cytokine production, and vascular leakage. A distinguishing feature of P. falciparum infection is parasite production and secretion of histidine...

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Detalles Bibliográficos
Autores principales: Pal, Priya, Daniels, Brian P., Oskman, Anna, Diamond, Michael S., Klein, Robyn S., Goldberg, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959673/
https://www.ncbi.nlm.nih.gov/pubmed/27273825
http://dx.doi.org/10.1128/mBio.00617-16