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Plasmodium falciparum Histidine-Rich Protein II Compromises Brain Endothelial Barriers and May Promote Cerebral Malaria Pathogenesis
Cerebral malaria (CM) is a disease of the vascular endothelium caused by Plasmodium falciparum. It is characterized by parasite sequestration, inflammatory cytokine production, and vascular leakage. A distinguishing feature of P. falciparum infection is parasite production and secretion of histidine...
Autores principales: | Pal, Priya, Daniels, Brian P., Oskman, Anna, Diamond, Michael S., Klein, Robyn S., Goldberg, Daniel E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959673/ https://www.ncbi.nlm.nih.gov/pubmed/27273825 http://dx.doi.org/10.1128/mBio.00617-16 |
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