Alkalosis and Dialytic Clearance of Phosphate Increases Phosphatase Activity: A Hidden Consequence of Hemodialysis

BACKGROUND: Extracellular pyrophosphate is a potent endogenous inhibitor of vascular calcification, which is degraded by alkaline phosphatase (ALP) and generated by hydrolysis of ATP via ectonucleotide pyrophosphatase/phosphodiesterase 1 (eNPP1). ALP activity (as routinely measured in clinical pract...

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Detalles Bibliográficos
Autores principales: Villa-Bellosta, Ricardo, González-Parra, Emilio, Egido, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959680/
https://www.ncbi.nlm.nih.gov/pubmed/27454315
http://dx.doi.org/10.1371/journal.pone.0159858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959680/
https://www.ncbi.nlm.nih.gov/pubmed/27454315
http://dx.doi.org/10.1371/journal.pone.0159858

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