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Tubular Overexpression of Angiopoietin-1 Attenuates Renal Fibrosis
Emerging evidence has highlighted the pivotal role of microvasculature injury in the development and progression of renal fibrosis. Angiopoietin-1 (Ang-1) is a secreted vascular growth factor that binds to the endothelial-specific Tie2 receptor. Ang-1/Tie2 signaling is critical for regulating blood...
Autores principales: | Singh, Sudhir, Manson, Scott R., Lee, Heedoo, Kim, Yeawon, Liu, Tuoen, Guo, Qiusha, Geminiani, Julio J., Austin, Paul F., Chen, Ying Maggie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959721/ https://www.ncbi.nlm.nih.gov/pubmed/27454431 http://dx.doi.org/10.1371/journal.pone.0158908 |
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