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Pharmacokinetics in Wistar Rats of 5-[(4-Carboxybutanoyl)Amino]-2-Hydroxybenzoic Acid: A Novel Synthetic Derivative of 5-Aminosalicylic Acid (5-ASA) with Possible Anti-Inflammatory Activity

5-[(4-carboxybutanoyl)amino]-2-hydroxybenzoic acid (C2) is a novel synthetic derivative of 5-aminosalicylic acid (5-ASA), which is currently being evaluated ex vivo as an anti-inflammatory agent and has shown satisfactory results. This study aimed to obtain the pharmacokinetic profiles, tissue distr...

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Detalles Bibliográficos
Autores principales:	Romero-Castro, Aurelio, Gutiérrez-Sánchez, Mara, Correa-Basurto, José, Rosales Hernández, Martha Cecilia, Padilla Martínez, Itzia Irene, Mendieta-Wejebe, Jessica Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959752/ https://www.ncbi.nlm.nih.gov/pubmed/27454774 http://dx.doi.org/10.1371/journal.pone.0159889

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