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Anticodon Modifications in the tRNA Set of LUCA and the Fundamental Regularity in the Standard Genetic Code

Based on (i) an analysis of the regularities in the standard genetic code and (ii) comparative genomics of the anticodon modification machinery in the three branches of life, we derive the tRNA set and its anticodon modifications as it was present in LUCA. Previously we proposed that an early ancest...

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Detalles Bibliográficos
Autores principales: van der Gulik, Peter T. S., Hoff, Wouter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959769/
https://www.ncbi.nlm.nih.gov/pubmed/27454314
http://dx.doi.org/10.1371/journal.pone.0158342